This leading research department is offering this grant to stimulate the development of innovative new treatments for genital herpes. This grant is for research focused on therapies that suppress viral shedding, reduce lesion formation, and ultimately decrease transmission in patients. Applications are invited for a broad range of therapeutic approaches, including but not limited to the development of new or improved antivirals, monoclonal antibodies, therapeutic vaccines, and gene editing technologies. The funding mechanism is a milestone-driven, biphasic award, where progression to the second phase is contingent upon successful completion of predefined milestones, ensuring a focused and progressive research pathway.
Opportunity ID: 356714
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-24-068 |
| Funding Opportunity Title: | New Therapeutic Strategies for Genital Herpes (R21/R33 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 15, 2024 |
| Last Updated Date: | Oct 15, 2024 |
| Original Closing Date for Applications: | Jan 31, 2025 |
| Current Closing Date for Applications: | Jan 31, 2025 |
| Archive Date: | Mar 08, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Private institutions of higher education City or township governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this notice of funding opportunity (NOFO) is to stimulate the development of new treatments for genital herpes that suppress shedding and lesion formation and reduce transmission. This NOFO invites applications that propose research into a broad range of therapeutic approaches, including but not limited to development of new or improved antivirals, monoclonal antibodies, therapeutic vaccines, and gene editing technologies for treatment of patients living with genital herpes. This NOFO will use a milestone-driven, biphasic award mechanism. Transition to the second phase is not guaranteed and will depend on the successful completion of milestones. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-24-068.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 356714 Full Announcement-RFA-AI-24-068 -> RFA-AI-24-068-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288409 | Dec 31, 2024 | Jan 31, 2025 | View |
Package 1
Mandatory forms
356714 RR_SF424_5_0-5.0.pdf
356714 PHS398_CoverPageSupplement_5_0-5.0.pdf
356714 RR_OtherProjectInfo_1_4-1.4.pdf
356714 PerformanceSite_4_0-4.0.pdf
356714 RR_KeyPersonExpanded_4_0-4.0.pdf
356714 RR_Budget10_3_0-3.0.pdf
356714 PHS398_ResearchPlan_5_0-5.0.pdf
356714 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
356714 RR_SubawardBudget10_30_3_0-3.0.pdf
356714 PHS_AssignmentRequestForm_4_0-4.0.pdf