This Medical Research Initiative offers a grant to advance research aimed at accelerating a Hepatitis B (HBV) cure in people living with HIV (PLWH). This funding opportunity seeks to better understand host and viral heterogeneity’s impact on HBV pathogenesis, persistence, and immunopathology, ultimately informing cure strategies. Applicants must establish multidisciplinary teams spanning clinical and basic/translational research. A key requirement is establishing an observational cohort to accelerate discovery and increase clinical impact, thereby improving outcomes for co-infected individuals. This grant is for supporting innovative research to overcome challenges in HBV cure for PLWH.
Opportunity ID: 350543
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-23-057 |
| Funding Opportunity Title: | Multidisciplinary Research to Accelerate Hepatitis B Cure in Persons Living with HIV and HBV (U19 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 10, 2023 |
| Last Updated Date: | Oct 10, 2023 |
| Original Closing Date for Applications: | Mar 13, 2024 |
| Current Closing Date for Applications: | Mar 13, 2024 |
| Archive Date: | Apr 18, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments State governments County governments Native American tribal governments (Federally recognized) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education For profit organizations other than small businesses Special district governments Public and State controlled institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to support research to better understand the impact of host and viral heterogeneity on pathogenesis of disease, viral persistence and immunopathology of Hepatitis B (HBV) and inform cure strategies for HBV in people living with HIV (PLWH). Applicants will establish multidisciplinary teams that span the clinical and basic/translational research arenas and establish an observational cohort to accelerate discovery and increase clinical impact. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-23-057.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350543 Full Announcement-RFA-AI-23-057 -> RFA-AI-23-057-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283414 | Feb 13, 2024 | Mar 13, 2024 | View |
Package 1
Mandatory forms
350543 RR_SF424_5_0-5.0.pdf
350543 PHS398_CoverPageSupplement_5_0-5.0.pdf
350543 RR_OtherProjectInfo_1_4-1.4.pdf
350543 PerformanceSite_4_0-4.0.pdf
350543 RR_KeyPersonExpanded_4_0-4.0.pdf
350543 PHS398_ResearchPlan_5_0-5.0.pdf
350543 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350543 PHS_Additional_IndirectCosts_2_0-2.0.pdf
350543 PHS_AssignmentRequestForm_3_0-3.0.pdf