The National Cancer Institute (NCI) offers this Coordinating Center grant for a new program on gastroesophageal cancer origins. This grant defines how these cancers evolve at the cellular level, leveraging advances in molecular classification, genomics, and stem cell research. The program investigates complex mechanisms driving tumor-initiating cell proliferation, focusing on gastric and gastroesophageal junction adenocarcinomas. Its core purpose is to outline the earliest cellular changes preceding histological manifestations or neoplasia. This U24 grant serves as the Coordinating Center for up to six associated R01 research grants, fostering comprehensive cancer initiation understanding.
Opportunity ID: 334354
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-21-027 |
| Funding Opportunity Title: | Coordinating Center for the Program on the Origins of Gastroesophageal Cancers (U24 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.396 — Cancer Biology Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 25, 2021 |
| Last Updated Date: | Jun 25, 2021 |
| Original Closing Date for Applications: | Oct 08, 2021 |
| Current Closing Date for Applications: | Oct 08, 2021 |
| Archive Date: | Nov 13, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Special district governments Private institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education County governments Public housing authorities/Indian housing authorities City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Cancer Institute (NCI) is publishing this Funding Opportunity Announcement (FOA) to request applications for the Coordinating Center, Program on the Origins of Gastroesophageal Cancers (U24). This new program will build on recent molecular classifications of gastroesophageal cancers, significant understanding of their cancer genomics, and advances in stem cell research to examine and define how these related cancers initially evolve at the cellular level. The program will address the complex mechanisms and effectors that direct the proliferation and expansion of tumor-initiating cells and their progeny to initiate these cancers. The focus of the FOA is on gastric and gastroesophageal junction adenocarcinomas. The program is envisioned to provide unprecedented opportunities to outline the earliest cellular changes in transformation that precede any histological manifestations or neoplasia. This new program will be composed of up to six large R01 research grants (to be supported by RFA-CA-21-026) and one Coordinating Center grant (to be supported by this FOA). |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-21-027.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00267949 | Sep 08, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
334354 RR_SF424_2_0-2.0.pdf
334354 PHS398_CoverPageSupplement_5_0-5.0.pdf
334354 RR_OtherProjectInfo_1_4-1.4.pdf
334354 PerformanceSite_2_0-2.0.pdf
334354 RR_KeyPersonExpanded_2_0-2.0.pdf
334354 RR_Budget_1_4-1.4.pdf
334354 PHS398_ResearchPlan_4_0-4.0.pdf
334354 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
334354 RR_SubawardBudget30_1_4-1.4.pdf
334354 PHS_AssignmentRequestForm_3_0-3.0.pdf
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