The National Cancer Institute (NCI) is offering this grant to support research within the Alliance of Glycobiologists for Detection of Cancer. This funding opportunity solicits applications for projects focused on understanding how changes in cellular carbohydrates contribute to cancer development and progression. The core purpose of this grant is to identify glycan-based abnormalities that can serve as promising biomarkers for early cancer detection or risk assessment. Studies may investigate glycoproteins, glycolipids, glycosaminoglycans, or their binding proteins. Proposed projects must demonstrate the ability of these biomarker candidates to accurately differentiate individuals with cancer from healthy ones. While clinical validation is ultimately expected, it is not required for the current projects. Awardees must also engage in collaborative, trans-Alliance activities.
Opportunity ID: 109074
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-11-009 |
| Funding Opportunity Title: | Alliance of Glycobiologists for Detection of Cancer (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 28, 2011 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Oct 07, 2011 |
| Current Closing Date for Applications: | Oct 07, 2011 |
| Archive Date: | Nov 07, 2011 |
| Estimated Total Program Funding: | $3,500,000 |
| Award Ceiling: | $350,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign (non-U.S.) components on applications submitted by U.S. Organizations are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to continue support for the program referred to as the Alliance of Glycobiologists for Detection of Cancer (http://glycomics.cancer.gov). Through this FOA, the NCI solicits new and competing renewal applications for research projects to elucidate how changes in cellular carbohydrates may promote cancer initiation and progression and use this information to identify glycan-based abnormalities that have the potential to serve as biomarkers for early cancer detection or risk assessment. These changes may be studied at the level of glycoproteins, glycolipids, glycosaminoglycans, and/or their binding proteins. The proposed projects must also address the ability of these biomarker candidates to accurately distinguish individuals with cancer from those without. It is expected that the most promising biomarker candidates will ultimately be tested in clinical validation studies, although such validation studies are not required for the proposed projects. In addition to planning for the individual research projects, the applicants responding to this FOA must plan for the participation in trans-Alliance activities, including collaborative projects with other awardees. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-11-009.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B2 | ADOBE-FORMS-B2 | PKG00067490 | Sep 07, 2011 | Oct 07, 2011 | View |
Package 1
Mandatory forms
109074 RR_SF424_1_2-1.2.pdf
109074 PerformanceSite_1_4-1.4.pdf
109074 RR_OtherProjectInfo_1_3-1.3.pdf
109074 RR_KeyPersonExpanded_1_2-1.2.pdf
109074 PHS398_CoverPageSupplement_1_4-1.4.pdf
109074 PHS398_ResearchPlan_1_3-1.3.pdf
109074 PHS398_Checklist_1_3-1.3.pdf
Optional forms
109074 RR_SubawardBudget30-1.2.pdf
109074 PHS398_ModularBudget_1_2-1.2.pdf
109074 RR_Budget-1.1.pdf
109074 PHS_CoverLetter_1_2-1.2.pdf
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