Opportunity ID: 357015

General Information

Document Type: Grants Notice
Funding Opportunity Number: PAR-25-145
Funding Opportunity Title: Clinical Characterization of Cancer Therapy-induced Adverse Sequelae and Mechanism-based Interventional Strategies (R01 Clinical Trial Optional)
Opportunity Category: Discretionary
Opportunity Category Explanation:
Funding Instrument Type: Grant
Category of Funding Activity: Education
Health
Category Explanation:
Expected Number of Awards:
Assistance Listings: 93.393 — Cancer Cause and Prevention Research
Cost Sharing or Matching Requirement: No
Version: Synopsis 1
Posted Date: Nov 06, 2024
Last Updated Date: Nov 06, 2024
Original Closing Date for Applications: Jan 07, 2028
Current Closing Date for Applications: Jan 07, 2028
Archive Date: Feb 12, 2028
Estimated Total Program Funding:
Award Ceiling:
Award Floor:

Eligibility

Eligible Applicants: Native American tribal governments (Federally recognized)
Independent school districts
Private institutions of higher education
Public housing authorities/Indian housing authorities
For profit organizations other than small businesses
State governments
Public and State controlled institutions of higher education
Special district governments
Native American tribal organizations (other than Federally recognized tribal governments)
County governments
Others (see text field entitled “Additional Information on Eligibility” for clarification)
City or township governments
Small businesses
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Additional Information on Eligibility: Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Additional Information

Agency Name: National Institutes of Health
Description: The purpose of this Funding Opportunity Announcement (FOA) is to support collaborative research projects designed to address adverse sequelae of cancer therapies that persist and become chronic comorbidities or develop as delayed posttreatment effects. This FOA supports basic, translational, and clinical research projects that seek to identify the mechanisms of therapy-induced adverse sequelae, clinically characterize the adverse sequelae, or translate the mechanistic understanding into therapeutic approaches to prevent or minimize the development of long-term sequelae. Research projects should focus on mechanistic studies with translational endpoints and longitudinal clinical phenotyping to identify and validate clinical endpoints (biomarkers, imaging, patient-reported outcomes, or combined elements) for future use in clinical trials that will evaluate the efficacy of interventions designed to prevent or reduce specific adverse sequelae.
Link to Additional Information: https://grants.nih.gov/grants/guide/pa-files/PAR-25-145.html
Grantor Contact Information: If you have difficulty accessing the full announcement electronically, please contact:

NIH Grants Information
grantsinfo@nih.gov
Email:grantsinfo@nih.gov

Version History

Version Modification Description Updated Date

Folder 357015 Full Announcement-PAR-25-145 -> PAR-25-145-Full-Announcement.pdf

Packages

Agency Contact Information: NIH Grants Information
grantsinfo@nih.gov
Email: grantsinfo@nih.gov
Who Can Apply: Organization Applicants

Assistance Listing Number Competition ID Competition Title Opportunity Package ID Opening Date Closing Date Actions
FORMS-I Use for due dates on or after January 25, 2025 PKG00288553 Jan 05, 2025 Jan 07, 2028 View

Package 1

Mandatory forms

357015 RR_SF424_5_0-5.0.pdf

357015 PHS398_CoverPageSupplement_5_0-5.0.pdf

357015 RR_OtherProjectInfo_1_4-1.4.pdf

357015 PerformanceSite_4_0-4.0.pdf

357015 RR_KeyPersonExpanded_4_0-4.0.pdf

357015 PHS398_ResearchPlan_5_0-5.0.pdf

357015 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf

Optional forms

357015 RR_Budget_3_0-3.0.pdf

357015 RR_SubawardBudget30_3_0-3.0.pdf

357015 PHS398_ModularBudget_1_2-1.2.pdf

357015 PHS_AssignmentRequestForm_4_0-4.0.pdf

2025-07-13T11:58:35-05:00

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