The National Cancer Institute (NCI) offers grants for Human Tumor Atlas (HTA) Research Centers as part of the Human Tumor Atlas Network (HTAN). This initiative aims to construct 3D and dynamic atlases of human cancers and their microenvironments, from precancerous lesions to advanced disease. Each HTA Research Center will create one precancer or advanced cancer atlas, specifically focusing on how evolving spatial relationships drive critical transitions in cancer, from tumor initiation to metastasis. Successful applicants will be responsible for biospecimen acquisition and annotation, comprehensive molecular, cellular, and spatial characterization, and robust data processing, analysis, modeling, and visualization. This grant supports deep understanding of cancer progression through detailed spatial mapping.
Opportunity ID: 350466
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-23-039 |
| Funding Opportunity Title: | Human Tumor Atlas (HTA) Research Centers (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Oct 04, 2023 |
| Last Updated Date: | Oct 04, 2023 |
| Original Closing Date for Applications: | Dec 05, 2023 |
| Current Closing Date for Applications: | Dec 05, 2023 |
| Archive Date: | Jan 10, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $800,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses City or township governments State governments Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities County governments Private institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for Human Tumor Atlas (HTA) Research Centers, one of the three scientific components of the Human Tumor Atlas Network (HTAN) (NCI Human Tumor Atlas Network). HTAN is a collaborative research initiative for constructing 3-dimensional(3D) and dynamic atlases of the cellular, morphological, molecular, and spatial features of human cancers and their surrounding microenvironments as they progress from precancerous lesions to advanced disease.Each HTA Research Center will construct one human precancer or advanced cancer atlas with an explicit focus on how evolving spatial relationships contribute to important transitions in cancer from tumor initiation to metastasis.The other two HTAN components are Precancer Atlas (PCA) Research Centers and a Data Coordinating Center (DCC). Each PCA Research Center will construct one 3D precancer atlas that comprehensively characterizes a premalignant lesion with an explicit focus on understanding the transition from a precancerous lesion to malignancy.The DCC will serve the dual role of network and data coordination. It will also be responsible for meeting coordination.Research Centers have three major areas of responsibility: (1) biospecimen acquisition, processing, and annotation, (2) molecular, cellular, and spatial characterization, and (3) data processing, analysis, modeling, and visualization. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-23-039.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 350466 Full Announcement-RFA-CA-23-039 -> RFA-CA-23-039-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00283365 | Nov 05, 2023 | Dec 05, 2023 | View |
Package 1
Mandatory forms
350466 RR_SF424_5_0-5.0.pdf
350466 PHS398_CoverPageSupplement_5_0-5.0.pdf
350466 RR_OtherProjectInfo_1_4-1.4.pdf
350466 PerformanceSite_4_0-4.0.pdf
350466 RR_KeyPersonExpanded_4_0-4.0.pdf
350466 PHS398_ResearchPlan_5_0-5.0.pdf
350466 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
350466 RR_Budget_3_0-3.0.pdf
350466 RR_SubawardBudget30_3_0-3.0.pdf
350466 PHS398_ModularBudget_1_2-1.2.pdf
350466 PHS_AssignmentRequestForm_3_0-3.0.pdf
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