This National Cancer Institute grant is for advancing translational research in early liver cancer detection. Its purpose is to establish Translational Research Centers (TRCs) to improve surveillance for high-risk populations, increase early-stage detection, and better stratify patient risk. Collaboration includes creating an integrated blood and image repository with clinical data. TRCs need multidisciplinary expertise in early cancer detection, biomarkers, and imaging. Centers will form a Liver Cancer Consortium, collaborating closely with a Data Management and Coordinating Center to achieve vital research goals.
Opportunity ID: 343153
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-22-031 |
| Funding Opportunity Title: | Consortium on Translational Research in Early Detection of Liver Cancer: Translational Research Centers (U01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | 5 |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 16, 2022 |
| Last Updated Date: | Aug 16, 2022 |
| Original Closing Date for Applications: | Nov 07, 2022 |
| Current Closing Date for Applications: | Nov 07, 2022 |
| Archive Date: | Dec 13, 2022 |
| Estimated Total Program Funding: | $4,400,000 |
| Award Ceiling: | $550,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Private institutions of higher education City or township governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Independent school districts Public and State controlled institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Small businesses State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) is soliciting applications for a Liver Cancer Consortium focused on advancing translational research in the early detection of liver cancer. Translational Research Centers (TRCs) will conduct studies to improve the surveillance of liver cancer in members of high-risk populations, increase the fraction of liver cancer detected at an early stage, and better stratify patients at risk of developing liver cancer. A major collaborative effort of the TRCs will be establishing an integrated blood and image repository with annotated clinical data from patients found to have indeterminate nodules during liver cancer surveillance. To achieve these goals, each proposed TRC should include laboratory and clinical researchers with multi-disciplinary expertise in such areas as early cancer detection, biomarkers, cancer surveillance, imaging, and biospecimen science. The Consortium will consist of several Translational Research Centers (TRCs, to be supported by this U01 FOA) and a Data Management and Coordinating Center (DMCC, to be supported a companion U24 FOA, RFA-CA-21-032). The TRCs will be expected to interact closely with the DMCC and engage in collaborative activities with other members of the Liver Cancer Consortium. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-22-031.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343153 Full Announcement-RFA-CA-22-031 -> RFA-CA-22-031-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00276451 | Oct 07, 2022 | Nov 07, 2022 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277976 | Nov 04, 2022 | Nov 07, 2022 | View |
Package 1
Mandatory forms
343153 RR_SF424_5_0-5.0.pdf
343153 PHS398_CoverPageSupplement_5_0-5.0.pdf
343153 RR_OtherProjectInfo_1_4-1.4.pdf
343153 PerformanceSite_4_0-4.0.pdf
343153 RR_KeyPersonExpanded_4_0-4.0.pdf
343153 PHS398_ResearchPlan_4_0-4.0.pdf
343153 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343153 RR_Budget_3_0-3.0.pdf
343153 RR_SubawardBudget30_3_0-3.0.pdf
343153 PHS398_ModularBudget_1_2-1.2.pdf
343153 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343153 RR_SF424_5_0-5.0.pdf
343153 PHS398_CoverPageSupplement_5_0-5.0.pdf
343153 RR_OtherProjectInfo_1_4-1.4.pdf
343153 PerformanceSite_4_0-4.0.pdf
343153 RR_KeyPersonExpanded_4_0-4.0.pdf
343153 PHS398_ResearchPlan_5_0-5.0.pdf
343153 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343153 RR_Budget_3_0-3.0.pdf
343153 RR_SubawardBudget30_3_0-3.0.pdf
343153 PHS398_ModularBudget_1_2-1.2.pdf
343153 PHS_AssignmentRequestForm_3_0-3.0.pdf
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