The National Cancer Institute is offering a grant to develop research resources for optimizing Quantitative Imaging methods in co-clinical trials. The grant aims to improve imaging quality by optimizing pre-clinical quantitative imaging methods, implementing them in co-clinical trials, and creating a web-accessible research resource with comprehensive data. Co-clinical trials involve investigations in both patients and mouse or human-in-mouse cancer models, focusing on therapeutic goals or cancer risk stratification. Applicants should form multidisciplinary teams proficient in mouse models research, human investigations, imaging platforms, and informatics. Deadline for application submission is June 14, 2021.
Opportunity ID: 306651
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-18-841 |
| Funding Opportunity Title: | Oncology Co-Clinical Imaging Research Resources to Encourage Consensus on Quantitative Imaging Methods and Precision Medicine (U24 – Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.394 — Cancer Detection and Diagnosis Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 28, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jun 14, 2021 |
| Current Closing Date for Applications: | Jun 14, 2021 |
| Archive Date: | Jul 20, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts For profit organizations other than small businesses Public housing authorities/Indian housing authorities Private institutions of higher education Small businesses City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to invite Cooperative Agreement applications to develop research resources that will encourage a consensus on how Quantitative Imaging (QI) methods are optimized to improve the quality of imaging results for co-clinical trials. The scientific goals of this FOA are to: (a) perform the appropriate optimization of the pre-clinical quantitative imaging methods, (b) implement the optimized methods in the co-clinical trial, and finally (c) populate a web-accessible research resource with all the data, methods, workflow documentation, and results collected from the co-clinical investigations. Co-clinical trials are defined in this FOA as investigations in patients and in parallel (or sequentially) in mouse or human-in-mouse models of cancer that mirror the genetics and biology of the patients malignancies or pre-cancerous lesions. The co-clinical trial should include either (a) a therapeutic goal, such as the prediction, staging, and/or measurement of tumor response to therapies, or (b) a screening and early detection or a cancer risk stratification goal for lethal cancer versus non-lethal disease. Applicants are encouraged to organize multi-disciplinary teams with experience in mouse models research, human investigations, imaging platforms, QI methods, decision support software and informatics to populate the research resource. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-18-841.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00243445 | Oct 19, 2018 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00258945 | Oct 19, 2018 | Jun 14, 2021 | View |
Package 1
Mandatory forms
306651 RR_SF424_2_0-2.0.pdf
306651 PHS398_CoverPageSupplement_4_0-4.0.pdf
306651 RR_OtherProjectInfo_1_4-1.4.pdf
306651 PerformanceSite_2_0-2.0.pdf
306651 RR_KeyPersonExpanded_2_0-2.0.pdf
306651 RR_Budget_1_4-1.4.pdf
306651 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
306651 RR_SubawardBudget30_1_4-1.4.pdf
306651 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
306651 RR_SF424_2_0-2.0.pdf
306651 PHS398_CoverPageSupplement_5_0-5.0.pdf
306651 RR_OtherProjectInfo_1_4-1.4.pdf
306651 PerformanceSite_2_0-2.0.pdf
306651 RR_KeyPersonExpanded_2_0-2.0.pdf
306651 RR_Budget_1_4-1.4.pdf
306651 PHS398_ResearchPlan_4_0-4.0.pdf
306651 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
306651 RR_SubawardBudget30_1_4-1.4.pdf
306651 PHS_AssignmentRequestForm_3_0-3.0.pdf
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