The National Cancer Institute (NCI) offers a U01 cooperative agreement to study estrogen receptor (ER)-negative breast cancers. This grant aims to characterize molecular features and growth pathways, informing early detection and intervention. Funding supports interdisciplinary research on ER-negative cancer biology, distinguishing it from ER-positive types and identifying subtypes. A key objective is determining biological differences in ER-negative tumors across diverse racial and ethnic groups, investigating their drivers. The NCI plans to commit approximately $10 million over five years, funding up to three awards.
Opportunity ID: 49073
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-CA-09-026 |
| Funding Opportunity Title: | The Biology of Estrogen Receptor-Negative Breast Cancer in Various Racial and Ethnic Groups (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.396 — Cancer Biology Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 13, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 05, 2010 |
| Current Closing Date for Applications: | Jan 05, 2010 |
| Archive Date: | Feb 05, 2010 |
| Estimated Total Program Funding: | $2,000,000 |
| Award Ceiling: | $667,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments For profit organizations other than small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education County governments Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Regional Organizations; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose.The purpose of this funding opportunity announcement (FOA) is to promote the systematic study of the biology of estrogen receptor (ER)-negative human breast cancers, the characterization of their molecular features, the signaling pathways and networks that support their growth, as well as to identify differences in the biology of ER-negative breast tumors among racial and ethnic groups. The information will be crucial in developing early detection and intervention strategies. This initiative will support studies on: the basic biology of ER-negative breast cancers and delineation of differences that exist between ER-positive and ER-negative breast cancers; the identification of the subtypes or heterogeneity that exist within ER-negative breast cancers; and the determination of whether the biology of ER-negative breast tumors differs across racial and ethnic groups. In order to address these goals, the National Cancer Institute (NCI) solicits applications from collaborative teams of interdisciplinary investigators focused on characterizing the biologic drivers, including genetic, epigenetic, molecular, and cellular factors, of ER-negative human breast cancer development and progression. Mechanism of Support. This FOA will utilize the NIH U01 cooperative agreement mechanism. Funds Available and Anticipated Number of Awards. The NCI expects to commit approximately $10 million for 5 years to fund up to three awards. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-CA-09-026.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
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