The National Cancer Institute is offering a grant to investigate the impact of early-life factors on cancer development later in life. The research aims to identify factors during various life stages that influence later cancer risk, understand the biological mechanisms linking early-life events to carcinogenesis, and develop predictive markers for cancer risk assessment and prevention strategies. This grant seeks to advance knowledge on how interventions during pregnancy and early life can effectively prevent cancer. The closing date for applications is on Jan 07, 2021.
Opportunity ID: 299547
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-18-531 |
| Funding Opportunity Title: | Early-life Factors and Cancer Development Later in Life (R03 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 20, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2021 |
| Current Closing Date for Applications: | Jan 07, 2021 |
| Archive Date: | Feb 12, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $50,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) County governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Public and State controlled institutions of higher education Small businesses Special district governments Public housing authorities/Indian housing authorities Private institutions of higher education City or township governments For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Funding Opportunity Announcement (FOA) is to stimulate research focused on the role of early-life factors (maternal-paternal, in utero, birth and infancy, puberty, adolescence, and young adult years) in cancer development later in life. Given that the current emerging evidence from limited research indicates a potentially important role for early-life events and exposures in cancer development, it is necessary to better understand 1) the early-life (maternal-paternal, in utero, birth and infancy, puberty, adolescence, and young adult years) factors that are associated with later cancer development; 2) how early-life factors mediate biological processes relevant to carcinogenesis; and 3) whether predictive markers for cancer risk based on what happens biologically at early life can be measured and developed for use in cancer prevention strategies. Markers that predict malignancy or pre-malignant conditions would allow assessment of early-life exposures with relevant outcomes without having to wait decades for cancer development. Ultimately, a better mechanistic understanding of how early-life events and exposures contribute to the etiology of cancer later in life will allow for the development of effective interventions during pregnancy or early life that may have a profound impact on cancer prevention. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-18-531.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00237179 | Jan 16, 2018 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00259676 | Jan 16, 2018 | Jan 07, 2021 | View |
Package 1
Mandatory forms
299547 RR_SF424_2_0-2.0.pdf
299547 PHS398_CoverPageSupplement_4_0-4.0.pdf
299547 RR_OtherProjectInfo_1_4-1.4.pdf
299547 PerformanceSite_2_0-2.0.pdf
299547 RR_KeyPersonExpanded_2_0-2.0.pdf
299547 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
299547 RR_Budget_1_4-1.4.pdf
299547 RR_SubawardBudget30_1_4-1.4.pdf
299547 PHS398_ModularBudget_1_2-1.2.pdf
299547 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
299547 RR_SF424_2_0-2.0.pdf
299547 PHS398_CoverPageSupplement_5_0-5.0.pdf
299547 RR_OtherProjectInfo_1_4-1.4.pdf
299547 PerformanceSite_2_0-2.0.pdf
299547 RR_KeyPersonExpanded_2_0-2.0.pdf
299547 PHS398_ResearchPlan_4_0-4.0.pdf
299547 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
299547 RR_Budget_1_4-1.4.pdf
299547 RR_SubawardBudget30_1_4-1.4.pdf
299547 PHS398_ModularBudget_1_2-1.2.pdf
299547 PHS_AssignmentRequestForm_3_0-3.0.pdf
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