The National Eye Institute (NEI) is offering a grant through the Audacious Goals Initiative for research focusing on the intersection of aging and biological mechanisms of eye disease. The grant aims to support innovative projects that explore the impact of aging on ocular health, the transition from aging to disease, disease pathophysiology, biomarker identification, and therapeutic advancements. Research areas include age-related macular degeneration, cataract, glaucoma, diabetic retinopathy, dry eye syndrome, and presbyopia. By better understanding the biological mechanisms underlying these conditions, new prevention and treatment strategies can be developed. Applications can encompass a range of research approaches and interdisciplinary collaborations.
Opportunity ID: 239801
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | PA-13-332 |
| Funding Opportunity Title:: | Audacious Goals Initiative High Priority Research Area: Intersection of Aging and Biological Mechanisms of Eye Disease (R01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Aug 13, 2013 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Jan 07, 2017 |
| Current Closing Date for Applications:: | Jan 07, 2017 |
| Archive Date:: | Feb 07, 2017 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | State governments |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The purpose of this Funding Opportunity Announcement (FOA) for the National Eye Institute (NEI) is to encourage submission of new, innovative projects directed to exploring this area through: 1) understanding how the biology of aging contributes to disease; 2) evaluating how the failure of homeostatic processes causes or allows the transition from aging to early disease; 3) defining the biological staging of disease to understand pathophysiology, identify biomarkers, and explore therapy; and 4) distinguishing normal ocular changes associated with aging from pathophysiologic changes. Advanced age is a risk factor for many of the leading causes of vision loss, including age-related macular degeneration, cataract, glaucoma, diabetic retinopathy, dry eye syndrome, and presbyopia. Better knowledge of the biological mechanisms of disease will lead to new strategies to prevent or delay progress of these age-related blinding conditions. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research. It is appropriate to propose small, multidisciplinary teams applying an integrative approach to solve these problems. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.866 |
| Competition ID: | FORMS-C |
| Competition Title: | Forms-C |
| Opportunity Package ID: | PKG00183055 |
| Opening Date: | Jan 05, 2014 |
| Closing Date: | May 07, 2016 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |
Package No: 2
| Assistance Listings: | |
| Competition ID: | FORMS-D |
| Competition Title: | Use for due dates on or after May 25, 2016 |
| Opportunity Package ID: | PKG00222098 |
| Opening Date: | Apr 17, 2016 |
| Closing Date: | Jan 07, 2017 |
| Agency Contact Information:: | eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/ |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Cover Page Supplement [V3.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] PHS 398 Research Plan [V3.0] |
| optional_forms |
Research & Related Budget [V1.3] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] PHS 398 Modular Budget [V1.2] PHS Inclusion Enrollment Report [V1.0] PHS Assignment Request Form [V1.0] |