This grant from the National Institute of Diabetes and Digestive and Kidney Diseases supports research to characterize and discover novel autoantigens and epitopes in type 1 diabetes. The focus is on studying the autoimmune responses triggered by these novel antigens and their impact on the development and progression of type 1 diabetes, integrating them with known autoantibodies such as those for insulin, GAD65, IA-2, and ZnT8T. Applications are open for innovative studies that can contribute to a better understanding of the etiology and pathophysiology of type 1 diabetes. Closing date for submissions is December 6, 2018.
Opportunity ID: 300710
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-17-031 |
| Funding Opportunity Title: | The Characterization and Discovery of Novel Autoantigens and Epitopes in Type 1 Diabetes (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 15, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 06, 2018 |
| Current Closing Date for Applications: | Dec 06, 2018 |
| Archive Date: | Jan 11, 2019 |
| Estimated Total Program Funding: | $1,250,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Special district governments State governments For profit organizations other than small businesses County governments Public housing authorities/Indian housing authorities Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research aimed at the characterization and discovery of neoantigens and neoepitopes in type 1 diabetes. These include the characterization of the humoral and cell mediated autoimmune responses elicited by these neoepitopes and neoantigens and their role in the etiology and pathophysiology of type 1 diabetes. These studies should be integrated with the present knowledge of established epitopes and antigens (e.g. autoantibodies for insulin, GAD65, IA-2, and ZnT8T). |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-17-031.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00238307 | Mar 26, 2018 | Dec 06, 2018 | View |
Package 1
Mandatory forms
300710 RR_SF424_2_0-2.0.pdf
300710 PHS398_CoverPageSupplement_4_0-4.0.pdf
300710 RR_OtherProjectInfo_1_4-1.4.pdf
300710 PerformanceSite_2_0-2.0.pdf
300710 RR_KeyPersonExpanded_2_0-2.0.pdf
300710 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
300710 RR_Budget_1_4-1.4.pdf
300710 RR_SubawardBudget30_1_4-1.4.pdf
300710 PHS398_ModularBudget_1_2-1.2.pdf
300710 PHS_AssignmentRequestForm_2_0-2.0.pdf
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