The National Institute of Health is offering a grant to establish research centers in pharmacogenomics for the advancement of precision medicine. The centers will focus on innovative studies to enhance understanding and prediction of therapeutic drug responses. Emphasizing data-driven prescribing, these multidisciplinary centers will serve as key hubs at the national and international level. Research themes will include exploration of gene expression patterns, post-genomic modifications, and small-molecule signatures to better predict drug actions. Applicants are encouraged to propose cutting-edge experimental approaches that extend beyond pharmacogenomics, aiming to revolutionize the field of precision medicine. Closing date for applications is May 28, 2015.
Opportunity ID: 250378
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-14-075 |
| Funding Opportunity Title: | Research Centers for Pharmacogenomics in Precision Medicine (P50) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jan 24, 2014 |
| Last Updated Date: | May 28, 2015 |
| Original Closing Date for Applications: | Sep 25, 2016 |
| Current Closing Date for Applications: | May 28, 2015 |
| Archive Date: | Jun 28, 2015 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $1,750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Native American tribal governments (Federally recognized) Special district governments Independent school districts Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Public housing authorities/Indian housing authorities State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to stimulate the formation of centers that will conduct cutting-edge research studies designed to push the boundaries for understanding and predicting therapeutic drug responses. The FOA describes research centers that examine drug actions within the context of precision medicine, or data-driven prescribing. This program will support a limited number of large-scale multidisciplinary centers, each of which will serve as a national and international focal point. A center should be built around a tightly-focused theme and should represent innovative investigations at the forefront of understanding drug actions. The experimental approaches should go beyond pharmacogenomics, to include for example, examination of gene expression and regulation patterns, assessment of post-genomic modifications, other small-molecule signatures that contribute to the prediction of drug actions both therapeutic and adverse, and/or systems and pathway analysis. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-14-075.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Modified the close date field, in accordance with NOT-GM-15-117. | May 28, 2015 | |
| May 28, 2015 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-14-075 |
| Funding Opportunity Title: | Research Centers for Pharmacogenomics in Precision Medicine (P50) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Jan 24, 2014 |
| Last Updated Date: | May 28, 2015 |
| Original Closing Date for Applications: | Sep 25, 2016 |
| Current Closing Date for Applications: | May 28, 2015 |
| Archive Date: | Jun 28, 2015 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $1,750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Native American tribal governments (Federally recognized) Special district governments Independent school districts Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) City or township governments Public housing authorities/Indian housing authorities State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to stimulate the formation of centers that will conduct cutting-edge research studies designed to push the boundaries for understanding and predicting therapeutic drug responses. The FOA describes research centers that examine drug actions within the context of precision medicine, or data-driven prescribing. This program will support a limited number of large-scale multidisciplinary centers, each of which will serve as a national and international focal point. A center should be built around a tightly-focused theme and should represent innovative investigations at the forefront of understanding drug actions. The experimental approaches should go beyond pharmacogenomics, to include for example, examination of gene expression and regulation patterns, assessment of post-genomic modifications, other small-molecule signatures that contribute to the prediction of drug actions both therapeutic and adverse, and/or systems and pathway analysis. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-14-075.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-14-075 |
| Funding Opportunity Title: | Research Centers for Pharmacogenomics in Precision Medicine (P50) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.859 — Biomedical Research and Research Training |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 28, 2015 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Sep 25, 2016 |
| Archive Date: | Oct 26, 2016 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $1,750,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Private institutions of higher education Independent school districts County governments Public housing authorities/Indian housing authorities City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this funding opportunity announcement (FOA) is to stimulate the formation of centers that will conduct cutting-edge research studies designed to push the boundaries for understanding and predicting therapeutic drug responses. The FOA describes research centers that examine drug actions within the context of precision medicine, or data-driven prescribing. This program will support a limited number of large-scale multidisciplinary centers, each of which will serve as a national and international focal point. A center should be built around a tightly-focused theme and should represent innovative investigations at the forefront of understanding drug actions. The experimental approaches should go beyond pharmacogenomics, to include for example, examination of gene expression and regulation patterns, assessment of post-genomic modifications, other small-molecule signatures that contribute to the prediction of drug actions both therapeutic and adverse, and/or systems and pathway analysis. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-14-075.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.859 | FORMS-C | Forms-C | PKG00192115 | Aug 25, 2014 | May 29, 2015 | View |
Package 1
Mandatory forms
250378 RR_SF424_2_0-2.0.pdf
250378 PHS398_CoverPageSupplement_2_0-2.0.pdf
250378 RR_KeyPersonExpanded_2_0-2.0.pdf
250378 RR_OtherProjectInfo_1_3-1.3.pdf
250378 PerformanceSite_2_0-2.0.pdf
250378 PHS398_ResearchPlan_2_0-2.0.pdf
Optional forms
250378 PHS_Additional_IndirectCosts-1.0.pdf
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