NIH is offering a grant to investigate the mechanistic and biological aspects of preneoplasias leading to lung, and head and neck (HN) cancers. This grant aims to enhance understanding of the molecular mechanisms behind the initiation and progression of preneoplasias to invasive cancer in order to develop more effective preventive and therapeutic strategies for lung and HN cancers, which continue to pose a significant health burden in the United States and globally. Applications focusing on early molecular markers of aerodigestive epithelial field injuries are encouraged to contribute to advancing knowledge in oncogenic progression.
Opportunity ID: 296507
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-17-459 |
| Funding Opportunity Title: | Biology of Lung, and Head and Neck Preneoplasias (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.396 — Cancer Biology Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 15, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2021 |
| Current Closing Date for Applications: | Jan 07, 2021 |
| Archive Date: | Feb 12, 2021 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses Public and State controlled institutions of higher education City or township governments Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments County governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) seeks applications investigating mechanistic and biological aspects of preneoplasia leading to lung, and head and neck (HN) cancers. Despite improved therapies and a deeper molecular understanding of lung and HN cancers, these tumors remain a major health problem in the United States and globally. While molecular markers of early injury to the aerodigestive epithelial field have been found, relatively little is known about the molecular mechanisms that initiate these preneoplasias and drive their progression to invasive cancer. A functional understanding of the key molecular changes involved in the formation and progression of lung and HN preneoplasias will enhance our knowledge of oncogenic progression and accelerate development of effective preventive and therapeutic strategies. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-17-459.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00235384 | Oct 27, 2017 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or after May 25, 2020 | PKG00259044 | Jan 05, 2018 | Jan 07, 2021 | View |
Package 1
Mandatory forms
296507 RR_SF424_2_0-2.0.pdf
296507 PHS398_CoverPageSupplement_4_0-4.0.pdf
296507 RR_OtherProjectInfo_1_4-1.4.pdf
296507 PerformanceSite_2_0-2.0.pdf
296507 RR_KeyPersonExpanded_2_0-2.0.pdf
296507 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
296507 RR_Budget_1_4-1.4.pdf
296507 RR_SubawardBudget30_1_4-1.4.pdf
296507 PHS398_ModularBudget_1_2-1.2.pdf
296507 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
296507 RR_SF424_2_0-2.0.pdf
296507 PHS398_CoverPageSupplement_5_0-5.0.pdf
296507 RR_OtherProjectInfo_1_4-1.4.pdf
296507 PerformanceSite_2_0-2.0.pdf
296507 RR_KeyPersonExpanded_2_0-2.0.pdf
296507 PHS398_ResearchPlan_4_0-4.0.pdf
296507 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
296507 RR_Budget_1_4-1.4.pdf
296507 RR_SubawardBudget30_1_4-1.4.pdf
296507 PHS398_ModularBudget_1_2-1.2.pdf
296507 PHS_AssignmentRequestForm_3_0-3.0.pdf
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