This grant from the National Institute of Heart, Lung, and Blood Institute aims to fund research investigating how female sex hormones and hormone-based therapies can increase the risk of thromboembolism in pre-menopausal women. The focus is on understanding the mechanisms underlying thrombosis in clinical scenarios like peripartum, contraceptive use, and in vitro fertilization. The research aims to identify high-risk women, improve clinical care, and discover potential new therapies to prevent thrombus formation. Excluded are studies on thromboembolism in post-menopausal women. Closing date for applications is June 20, 2017.
Opportunity ID: 291259
General Information
Document Type: | Grants Notice |
Funding Opportunity Number: | RFA-HL-18-003 |
Funding Opportunity Title: | Sex Hormone Induced Thromboembolism in Pre-Menopausal Women (R61/R33) |
Opportunity Category: | Discretionary |
Opportunity Category Explanation: | – |
Funding Instrument Type: | Grant |
Category of Funding Activity: | Health |
Category Explanation: | – |
Expected Number of Awards: | – |
Assistance Listings: | 93.839 — Blood Diseases and Resources Research |
Cost Sharing or Matching Requirement: | No |
Version: | Synopsis 1 |
Posted Date: | Jan 17, 2017 |
Last Updated Date: | – |
Original Closing Date for Applications: | Jun 20, 2017 |
Current Closing Date for Applications: | Jun 20, 2017 |
Archive Date: | Jul 21, 2017 |
Estimated Total Program Funding: | – |
Award Ceiling: | $475,000 |
Award Floor: | – |
Eligibility
Eligible Applicants: | Public and State controlled institutions of higher education State governments Native American tribal governments (Federally recognized) County governments Independent school districts For profit organizations other than small businesses Small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) |
Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
Agency Name: | National Institutes of Health |
Description: | The primary objective of the work to be supported by this funding opportunity is to understand the mechanisms by which female sex hormones and sex hormone-based therapies can increase the risk of venous and arterial thromboembolism in pre-menopausal women. Understanding the basic physiopathology of how sex hormones may induce or add to the pre-existing risk of thrombosis will strengthen our understanding of the mechanisms underlying thrombus formation in relevant clinical situations such as peripartum or in women using contraceptives or undergoing in vitro fertilization. Such research may help identify women at higher thrombotic risk and thus help guide their clinical care. It could also lead to the identification of potential new therapeutics to prevent thrombus formation. The FOA purpose does not include research on thromboembolism related comorbidities in post-menopausal women. |
Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-18-003.html |
Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
Version | Modification Description | Updated Date |
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Related Documents
There are no related documents on this grant.
Packages
Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
Who Can Apply: | Organization Applicants |
Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
---|---|---|---|---|---|---|
FORMS-D | Use for due dates on or after May 25, 2016 | PKG00230311 | May 20, 2017 | Jun 20, 2017 | View |
Package 1
Mandatory forms
291259 RR_SF424_2_0-2.0.pdf
291259 PHS398_CoverPageSupplement_3_0-3.0.pdf
291259 RR_OtherProjectInfo_1_3-1.3.pdf
291259 PerformanceSite_2_0-2.0.pdf
291259 RR_KeyPersonExpanded_2_0-2.0.pdf
291259 RR_Budget_1_3-1.3.pdf
291259 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
291259 RR_SubawardBudget30_1_3-1.3.pdf
291259 PHS_Inclusion_Enrollment_Report-1.0.pdf
291259 PHS_AssignmentRequestForm-1.0.pdf