This grant aims to fund projects focused on reducing the duration of untreated psychosis (DUP) in the United States, particularly among adolescents and young adults experiencing their first episode of psychosis. By supporting research that identifies baseline DUP rates, maps referral pathways, addresses bottlenecks in care, and pilots strategies to shorten DUP, the grant seeks to improve outcomes for individuals with psychotic disorders. The goal is to facilitate early identification, rapid referral, and effective engagement in team-based Coordinated Specialty Care (CSC) programs, ultimately aligning with the World Health Organization’s recommendation to reduce DUP to 3 months or less.
Opportunity ID: 298908
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-18-232 |
| Funding Opportunity Title: | Reducing the Duration of Untreated Psychosis in the United States (R34 Clinical Trial Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 21, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Mar 19, 2019 |
| Current Closing Date for Applications: | Mar 19, 2019 |
| Archive Date: | Apr 24, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $225,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Private institutions of higher education Independent school districts Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education County governments City or township governments Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Approximately 100,000 adolescents and young adults in the United States experience a first episode of psychosis (FEP) every year. The early phase of psychotic illness is widely viewed as a critical opportunity for indicated prevention, and a chance to alter the downward trajectory and poor outcomes associated with schizophrenia and related psychotic disorders. Compared to traditional treatment approaches, programs that integrate pharmacologic, psychological, and rehabilitation interventions for FEP, i.e., team-based Coordinated Specialty Care (CSC), have been found to produce a range of positive clinical and functional outcomes. However, the timing of treatment is critical; short and long-term outcomes are better when individuals begin treatment close to the onset of psychosis. Unfortunately, numerous studies find a substantial delay between the onset of psychotic symptoms and the initiation of FEP care; in the U.S. treatment is typically delayed between one and three years. Early identification of FEP, rapid referral to evidence-based services, and effective engagement in CSC are essential to shortening the duration of untreated psychosis (DUP) and pre-empting the functional deterioration common in psychotic disorders. The World Health Organization advocates reducing DUP to 3 months or less. Accordingly, this Funding Opportunity Announcement (FOA) seeks planning grant applications that (1) identify a baseline rate of DUP in community settings that include CSC programs; (2) map referral pathways to CSC care, (3) identify bottlenecks and gaps in the pathway to CSC care, and (4) develop and pilot test feasible strategies for substantially reducing DUP among persons with FEP. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-18-232.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00236452 | Feb 17, 2018 | Mar 19, 2019 | View |
Package 1
Mandatory forms
298908 RR_SF424_2_0-2.0.pdf
298908 PHS398_CoverPageSupplement_4_0-4.0.pdf
298908 RR_OtherProjectInfo_1_4-1.4.pdf
298908 PerformanceSite_2_0-2.0.pdf
298908 RR_KeyPersonExpanded_2_0-2.0.pdf
298908 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
298908 RR_Budget_1_4-1.4.pdf
298908 RR_SubawardBudget30_1_4-1.4.pdf
298908 PHS398_ModularBudget_1_2-1.2.pdf
298908 PHS_AssignmentRequestForm_2_0-2.0.pdf
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