This grant from the National Institute of Neurological Disorders and Stroke aims to support unbiased proteomics analysis in the Accelerating Medicine Partnership in Parkinson’s disease cohorts. The goal is to identify biomarkers for diagnosis, prognosis, and progression of Parkinson’s disease using matched longitudinal CSF and plasma samples analyzed through a DIA mass spectrometry platform. Generated proteomics data will be shared via the AMP PD Knowledge Portal for further research and integration. The analysis includes evaluating pre-analytical variables for optimal handling of 4,500 CSF and plasma samples. Closing date for applications is May 29, 2019.
Opportunity ID: 314562
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-19-028 |
| Funding Opportunity Title: | Accelerating Medicine Partnership in Parkinsons disease (AMP PD) unbiased proteomics biofluid analysis (U01 Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 05, 2019 |
| Last Updated Date: | Apr 05, 2019 |
| Original Closing Date for Applications: | May 29, 2019 |
| Current Closing Date for Applications: | May 29, 2019 |
| Archive Date: | Jul 04, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Small businesses Native American tribal governments (Federally recognized) For profit organizations other than small businesses Independent school districts Special district governments Public housing authorities/Indian housing authorities State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of the FOA is to support unbiased proteomics analysis of matched longitudinal CSF and plasma samples from the Accelerating Medicine Partnership in Parkinson’s disease (AMP PD) cohorts using a data independent acquisition (DIA) mass spectrometry platform, with the ultimate goal of identifying PD biomarkers for diagnosis, prognosis and progression. Proteomics data and workflows generated through this initiative will be broadly shared with the research community through the AMP PD Knowledge Portal to enable additional analyses and data integration across the various datatypes available through AMP PD. The proteomics analysis will be staged to include identification of pre-analytical variables, that will inform the optimal handling of 4,500 CSF and plasma samples. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-19-028.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00249736 | Apr 29, 2019 | May 29, 2019 | View |
Package 1
Mandatory forms
314562 RR_SF424_2_0-2.0.pdf
314562 PHS398_CoverPageSupplement_4_0-4.0.pdf
314562 RR_OtherProjectInfo_1_4-1.4.pdf
314562 PerformanceSite_2_0-2.0.pdf
314562 RR_KeyPersonExpanded_2_0-2.0.pdf
314562 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
314562 RR_Budget_1_4-1.4.pdf
314562 RR_SubawardBudget30_1_4-1.4.pdf
314562 PHS398_ModularBudget_1_2-1.2.pdf
314562 PHS_AssignmentRequestForm_2_0-2.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
