This grant is for studying the cellular and molecular mechanisms of HIV-associated neurocognitive disorder (HAND) in the context of long-term combination antiretroviral therapy (cART) using induced microglia and cerebral organoids derived from patient-specific induced pluripotent stem cells (iPSC). Researchers are encouraged to apply to unravel the neuropathophysiology of HAND under cART conditions. The closing date for applications is December 18, 2018.
Opportunity ID: 308858
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-19-010 |
| Funding Opportunity Title: | Modeling HIV Neuropathology Using Microglia from Human iPSC and Cerebral Organoids (R21-Clinical Trials Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 07, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 18, 2018 |
| Current Closing Date for Applications: | Dec 18, 2018 |
| Archive Date: | Jan 23, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Special district governments Public housing authorities/Indian housing authorities City or township governments Independent school districts Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal organizations (other than Federally recognized tribal governments) County governments Public and State controlled institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites research grant applications to study the cellular and molecular mechanisms delineating the neuropathophysiology of HAND in the setting of long-term combination antiretroviral therapy (cART) conditions using induced microglia and cerebral organoids generated from patient derived induced pluripotent stem cell (iPSC) lines. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-19-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00244750 | Nov 18, 2018 | Dec 18, 2018 | View |
Package 1
Mandatory forms
308858 RR_SF424_2_0-2.0.pdf
308858 PHS398_CoverPageSupplement_4_0-4.0.pdf
308858 RR_OtherProjectInfo_1_4-1.4.pdf
308858 PerformanceSite_2_0-2.0.pdf
308858 RR_KeyPersonExpanded_2_0-2.0.pdf
308858 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
308858 RR_Budget_1_4-1.4.pdf
308858 RR_SubawardBudget30_1_4-1.4.pdf
308858 PHS398_ModularBudget_1_2-1.2.pdf
308858 PHS_AssignmentRequestForm_2_0-2.0.pdf
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