The National Institute on Aging offers a grant to support the pre-clinical development of new therapies addressing behavioral symptoms in Alzheimer’s disease or delaying its onset. Projects should focus on optimizing therapeutic leads targeting AD, mild cognitive impairment, or age-related cognitive decline to potentially submit an application to the FDA by the funding period’s end. This milestone-driven cooperative program does not fund early-stage discovery or basic research, aiming solely at advancing treatment development for AD.
Opportunity ID: 130973
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | PAR-12-015 |
| Funding Opportunity Title:: | Alzheimer’s Disease Drug Development Program (U01) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Health |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Nov 16, 2011 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Jan 07, 2015 |
| Current Closing Date for Applications:: | Jan 07, 2015 |
| Archive Date:: | Feb 07, 2015 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Special district governments |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The goal of this funding opportunity announcement (FOA) is to support pre-clinical development of new therapies aimed at modifying the behavioral symptoms in Alzheimer’s disease (AD); or delaying the onset or slowing the progression of AD, mild cognitive impairment (MCI), or age-related cognitive decline. This program is specifically directed at projects focused on the optimization of therapeutic leads with demonstrated activity against an intended disease target. Projects must be sufficiently advanced that an IND or IDE application to the FDA can be submitted by the end of the funding period. The program does not support early-stage therapeutic discovery activities such as high throughput screening. The program also excludes clinical research and basic, mechanistic research. This is a milestone-driven cooperative agreement program involving participation of NIA program staff both in the development of the project plan and monitoring of research progress. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:
Package No: 1
| Assistance Listings: | 93.866 |
| Competition ID: | ADOBE-FORMS-B2 |
| Competition Title: | ADOBE-FORMS-B2 |
| Opportunity Package ID: | PKG00085790 |
| Opening Date: | Jan 05, 2012 |
| Closing Date: | Sep 24, 2013 |
| Agency Contact Information:: | Grants Info |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2] |
Package No: 2
| Assistance Listings: | 93.866 |
| Competition ID: | FORMS-C |
| Competition Title: | Use for due dates after 9/24/2013 |
| Opportunity Package ID: | PKG00180686 |
| Opening Date: | Sep 08, 2013 |
| Closing Date: | Jan 07, 2015 |
| Agency Contact Information:: | eRA Commons Help Desk |
| Who Can Apply:: | Organization Applicants |
| mendatory_forms |
SF424 (R & R) [V2.0] PHS 398 Research Plan [V2.0] PHS 398 Cover Page Supplement [V2.0] Research and Related Senior/Key Person Profile (Expanded) [V2.0] Research And Related Other Project Information [V1.3] Project/Performance Site Location(s) [V2.0] |
| optional_forms |
R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.3] Planned Enrollment Report [V1.0] PHS 398 Cumulative Inclusion Enrollment Report [V1.0] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.3] |