National Institute on Aging Grant for Age-Related Osteoimmunology Research (R01)

This grant from the National Institute on Aging (NIA) supports research projects focusing on age-related changes in osteoimmunology using animal models to investigate the impact of aging on the balance between bone metabolism and immune function. The aim is to enhance understanding of the immune and skeletal system interactions in the context of aging-related diseases, such as immune senescence and loss of bone homeostasis. Researchers in the field of osteoimmunology are encouraged to expand their work to address the knowledge gaps in aging aspects of osteoimmunology. Applications for this grant must be submitted by Feb 07, 2013.

Opportunity ID: 206474

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-AG-13-017
Funding Opportunity Title::	Age-Related Changes in Osteoimmunology (R01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.866 — Aging Research
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Nov 13, 2012
Last Updated Date::
Original Closing Date for Applications::	Feb 07, 2013
Current Closing Date for Applications::	Feb 07, 2013
Archive Date::	Mar 10, 2013
Estimated Total Program Funding::	$ 1,000,000
Award Ceiling::	$125,000
Award Floor::	$

Eligibility

Eligible Applicants::

Native American tribal organizations (other than Federally recognized tribal governments)

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	This Funding Opportunity Announcement (FOA), issued by the National Institute on Aging (NIA) at the National Institutes of Health, solicits grant applications that propose extension of research activities on osteoimmunology in order to broaden our understanding of aging aspects of osteoimmunology, using animal models. Most studies in this field have been conducted in young mouse models (usually animals less than 6 months of age). Under those conditions, it is not possible to ascertain the effects of aging in the balance between bone metabolism and immune function. Studies sought under this FOA should focus on the impact of the age-related decline in immune function on bone homeostasis or conversely on the age-related changes in the bone marrow niche affecting the immune interactions with bone. Research in osteoimmunology aims to understand the interplay between the immune and skeletal systems, and how these interactions lead to disease when disrupted. In the clinical setting, such disequilibria and the resulting diseases are most commonly found in the elderly, which are afflicted by both immune senescence and loss of bone homeostasis. This FOA is intended as a vehicle to allow investigators already working in the field of osteoimmunology to expand the scope of their research, so as to allow an enhanced understanding of the field within the context of the clinically relevant setting of aging.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:	93.866
Competition ID:	ADOBE-FORMS-B2
Competition Title:	Adobe-Forms-B2
Opportunity Package ID:	PKG00151690
Opening Date:	Jan 07, 2013
Closing Date:	Feb 07, 2013
Agency Contact Information::	eRA Commons Help Desk
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]