The National Institute on Aging (NIA) is offering this grant to support the pre-clinical development of new therapies. This grant is for projects focused on modifying behavioral symptoms in Alzheimer’s disease (AD), or delaying the onset or slowing the progression of AD, mild cognitive impairment (MCI), or age-related cognitive decline. The program specifically targets the optimization of therapeutic leads that have demonstrated activity against an intended disease target. Projects must be sufficiently advanced to allow for an IND or IDE application submission to the FDA by the funding period’s end. This milestone-driven cooperative agreement excludes early-stage therapeutic discovery, clinical research, and basic, mechanistic research, involving active participation from NIA program staff.
Opportunity ID: 130973
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-12-015 |
| Funding Opportunity Title: | Alzheimer’s Disease Drug Development Program (U01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Nov 16, 2011 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2015 |
| Current Closing Date for Applications: | Jan 07, 2015 |
| Archive Date: | Feb 07, 2015 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Special district governments Independent school districts Private institutions of higher education State governments Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this funding opportunity announcement (FOA) is to support pre-clinical development of new therapies aimed at modifying the behavioral symptoms in Alzheimer’s disease (AD); or delaying the onset or slowing the progression of AD, mild cognitive impairment (MCI), or age-related cognitive decline. This program is specifically directed at projects focused on the optimization of therapeutic leads with demonstrated activity against an intended disease target. Projects must be sufficiently advanced that an IND or IDE application to the FDA can be submitted by the end of the funding period. The program does not support early-stage therapeutic discovery activities such as high throughput screening. The program also excludes clinical research and basic, mechanistic research. This is a milestone-driven cooperative agreement program involving participation of NIA program staff both in the development of the project plan and monitoring of research progress. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-12-015.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.866 | ADOBE-FORMS-B2 | ADOBE-FORMS-B2 | PKG00085790 | Jan 05, 2012 | Sep 24, 2013 | View |
| 93.866 | FORMS-C | Use for due dates after 9/24/2013 | PKG00180686 | Sep 08, 2013 | Jan 07, 2015 | View |
Package 1
Mandatory forms
130973 RR_SF424_1_2-1.2.pdf
130973 PerformanceSite_1_4-1.4.pdf
130973 RR_OtherProjectInfo_1_3-1.3.pdf
130973 RR_KeyPersonExpanded_1_2-1.2.pdf
130973 PHS398_CoverPageSupplement_1_4-1.4.pdf
130973 PHS398_ResearchPlan_1_3-1.3.pdf
130973 PHS398_Checklist_1_3-1.3.pdf
Optional forms
130973 RR_SubawardBudget30-1.2.pdf
130973 PHS398_ModularBudget_1_2-1.2.pdf
130973 RR_Budget-1.1.pdf
130973 PHS_CoverLetter_1_2-1.2.pdf
Package 2
Mandatory forms
130973 RR_SF424_2_0-2.0.pdf
130973 PHS398_ResearchPlan_2_0-2.0.pdf
130973 PHS398_CoverPageSupplement_2_0-2.0.pdf
130973 RR_KeyPersonExpanded_2_0-2.0.pdf
130973 RR_OtherProjectInfo_1_3-1.3.pdf
130973 PerformanceSite_2_0-2.0.pdf
Optional forms
130973 RR_SubawardBudget30_1_3-1.3.pdf
130973 PlannedReport-1.0.pdf
130973 PHS398_CumulativeInclusionReport-1.0.pdf
130973 PHS398_ModularBudget_1_2-1.2.pdf
130973 RR_Budget_1_3-1.3.pdf
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