This grant opportunity from the National Institute on Aging seeks proposals for research studying exosome biogenesis and secretion in relation to the early stages of Alzheimer’s Disease. Emphasis is placed on collaborative projects that aim to uncover the regulation of molecular mechanisms involved in exosome formation and cargo secretion within the context of AD pathogenesis. Applicants are encouraged to explore innovative approaches in understanding the modulation and spread of early disease processes in both sporadic and late-onset AD.
Opportunity ID: 299438
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-18-027 |
| Funding Opportunity Title: | Exosomes: From Biogenesis and Secretion to the Early Pathogenesis of Alzheimer’s Disease (R01 – Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 15, 2017 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Mar 26, 2018 |
| Current Closing Date for Applications: | Mar 26, 2018 |
| Archive Date: | May 01, 2018 |
| Estimated Total Program Funding: | $8,000,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal governments (Federally recognized) Independent school districts State governments For profit organizations other than small businesses Public and State controlled institutions of higher education County governments Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Public housing authorities/Indian housing authorities |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites innovative research focused on understanding the role of exosome biogenesis and secretion in modulating and propagation of early pathogenesis in sporadic and late-onset Alzheimers disease (AD). Specifically, this FOA encourages collaborative approaches designed to identify and characterize the regulation of molecular machines that are responsible for exosome biogenesis and the secretion of exosomal cargo molecules in AD. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-18-027.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00237081 | Feb 23, 2018 | Mar 26, 2018 | View |
Package 1
Mandatory forms
299438 RR_SF424_2_0-2.0.pdf
299438 PHS398_CoverPageSupplement_4_0-4.0.pdf
299438 RR_OtherProjectInfo_1_4-1.4.pdf
299438 PerformanceSite_2_0-2.0.pdf
299438 RR_KeyPersonExpanded_2_0-2.0.pdf
299438 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
299438 RR_Budget_1_4-1.4.pdf
299438 RR_SubawardBudget30_1_4-1.4.pdf
299438 PHS398_ModularBudget_1_2-1.2.pdf
299438 PHS_AssignmentRequestForm_2_0-2.0.pdf
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