The National Institute on Aging is offering this grant to establish a network for transdisciplinary research into Alzheimer’s Disease (AD) and AD-Related Dementias (ADRD) diagnostics in older adults with Multiple Chronic Conditions (MCCs). This grant is for the purpose of better aligning diagnostic testing with the needs and priorities of the aging population. The national consortium will achieve this by assembling and acquiring diverse real-world data, including pre-specified subgroup analyses. Researchers will analyze this data to evaluate the performance and accuracy of various biomarkers, such as blood, cerebrospinal fluid, and imaging, specifically within older patients living with MCCs. Additionally, the network will conduct pilot studies exploring specific AD/ADRD imaging and/or biomarkers in this vulnerable population.
Opportunity ID: 341114
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-23-032 |
| Funding Opportunity Title: | Network for Personalization of Diagnostic Tests for Alzheimers Disease (AD) and Alzheimers Disease-Related Dementias (ADRD) in Older Adults with Multiple Chronic Conditions (MCCs) (U24 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 14, 2022 |
| Last Updated Date: | Jun 14, 2022 |
| Original Closing Date for Applications: | Oct 17, 2022 |
| Current Closing Date for Applications: | Oct 17, 2022 |
| Archive Date: | Nov 22, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $1,150,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Private institutions of higher education Public housing authorities/Indian housing authorities City or township governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) State governments Special district governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) invites applications to establish a network that will conduct transdisciplinary aging diagnostic biomarker and/or imaging research projects focused on Alzheimers Disease and Alzheimers Disease-Related Dementias (AD/ADRD) in persons living with Multiple Chronic Conditions (MCCs). The aim of the research is to better align diagnostic testing with the needs and priorities of an aging population. The national consortium will: 1) assemble existing data and acquire real-world data to ensure that the research sample is large and diverse, with adequate representation of older adults living with well-characterized MCCs, and incorporate pre-specified subgroup analyses; 2) analyze data for performance and accuracy of biomarkers, to include blood, cerebrospinal fluid (CSF), and imaging, in older patients living with MCCs; and 3) conduct pilot studies involving specific AD/ADRD imaging and/or biomarkers in persons living with MCCs. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-23-032.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 341114 Full Announcement-RFA-AG-23-032 -> RFA-AG-23-032-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00274980 | Sep 17, 2022 | Oct 17, 2022 | View |
Package 1
Mandatory forms
341114 RR_SF424_5_0-5.0.pdf
341114 PHS398_CoverPageSupplement_5_0-5.0.pdf
341114 RR_OtherProjectInfo_1_4-1.4.pdf
341114 PerformanceSite_4_0-4.0.pdf
341114 RR_KeyPersonExpanded_4_0-4.0.pdf
341114 RR_Budget_3_0-3.0.pdf
341114 PHS398_ResearchPlan_4_0-4.0.pdf
341114 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
341114 RR_SubawardBudget30_3_0-3.0.pdf
341114 PHS_AssignmentRequestForm_3_0-3.0.pdf
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