The National Institute on Aging is offering a research grant to support the structural characterization of protein species associated with Alzheimer’s Disease Related Dementias (ADRDs) using cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET). Applicants are expected to study proteins expressed in human tissues and cells, develop research tools, and resources to validate protein species. This grant aims to address the challenges of Alzheimer’s Disease Related Dementias (ADRD) as per the 2016 update to the National Plan to Address Alzheimer’s Disease. Closing date for applications is April 30, 2018.
Opportunity ID: 300558
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-NS-18-015 |
| Funding Opportunity Title: | Structural Biology of Alzheimer’s Disease Related Dementias (ADRDs) Proteinopathies (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 07, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Apr 30, 2018 |
| Current Closing Date for Applications: | Apr 30, 2018 |
| Archive Date: | Jun 05, 2018 |
| Estimated Total Program Funding: | $2,500,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Private institutions of higher education Native American tribal governments (Federally recognized) County governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Public and State controlled institutions of higher education Small businesses Special district governments For profit organizations other than small businesses City or township governments Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of the FOA is to support the structural characterization of protein species associated with Alzheimer’s Disease Related Dementias (ADRDs) through the utilization of cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) of proteins expressed in human tissue and cell sources. Studies in response to this RFA should also include the development of research tools and resources to further characterize/validate the protein species. This FOA is in response to the Alzheimer’s Disease Related Dementias (ADRD) challenges outlined in the 2016 update to the National Plan to Address Alzheimer’s Disease. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-18-015.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or after January 25, 2018 | PKG00238119 | Mar 30, 2018 | Apr 30, 2018 | View |
Package 1
Mandatory forms
300558 RR_SF424_2_0-2.0.pdf
300558 PHS398_CoverPageSupplement_4_0-4.0.pdf
300558 RR_OtherProjectInfo_1_4-1.4.pdf
300558 PerformanceSite_2_0-2.0.pdf
300558 RR_KeyPersonExpanded_2_0-2.0.pdf
300558 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
300558 RR_Budget_1_4-1.4.pdf
300558 RR_SubawardBudget30_1_4-1.4.pdf
300558 PHS398_ModularBudget_1_2-1.2.pdf
300558 PHS_AssignmentRequestForm_2_0-2.0.pdf
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