The National Institute on Aging is offering a grant for the development of research planning infrastructure to identify therapeutic targets based on genetic factors associated with human longevity or health span. The project involves creating databases, tools, and conducting analyses to identify genes or molecules that could positively influence lifespan. Expertise in genetics, genomics, epidemiology, and drug development is crucial for the multidisciplinary team. Funding for implementing the target identification strategies may be available through future FOAs, while new genetic studies are not within the scope of this opportunity.
Opportunity ID: 261792
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AG-15-014 |
| Funding Opportunity Title: | Research Planning Infrastructure to Develop Therapeutic Target-ID Strategies Based on Favorable Genetic Variants of Human Longevity or Health Span (U24) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | 1 |
| Assistance Listings: | 93.866 — Aging Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 13, 2014 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Nov 06, 2014 |
| Current Closing Date for Applications: | Nov 06, 2014 |
| Archive Date: | Dec 07, 2014 |
| Estimated Total Program Funding: | $1,000,000 |
| Award Ceiling: | $700,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education County governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Small businesses Native American tribal governments (Federally recognized) State governments Public housing authorities/Indian housing authorities For profit organizations other than small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA invites applications for a project for the development of a research planning infrastructure by a multidisciplinary collaborative team to develop target identification (ID) strategies based on effects of genetic factors reliably associated with increased human lifespan and/or health span. The phrase “target ID strategy” refers to a concerted set of applied research approaches (e.g., additional analyses, conducting required types of studies/ experiments and methodologies in the appropriate sequence) leading to the identification of genetic factors, pathways, or molecules by which activities could be favorably modified. Planning activities to be conducted by the U24 project include the creation of an integrated database of relevant data, informatics and computational tools for assessing the effects of favorable gene variants, evaluating their potential utility for developing therapeutic ID strategies, developing plans for experiments and analyses aimed at identifying one or more therapeutic target(s) and establishing a publicly available resource. Core areas of expertise which should be represented in the U24 multidisciplinary team include genetics, genomics, epidemiology, aging research, translational genomics, drug development, statistics, and bioinformatics.
Support for implementation of the target identification strategies developed by the U24 project could be requested in the future through other FOAs. New population or family studies on genetic factors influencing longevity are also outside the scope of this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-15-014.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | FORMS-C | PKG00203187 | Oct 06, 2014 | Nov 06, 2014 | View |
Package 1
Mandatory forms
261792 RR_SF424_2_0-2.0.pdf
261792 PHS398_ResearchPlan_2_0-2.0.pdf
261792 PHS398_CoverPageSupplement_2_0-2.0.pdf
261792 RR_Budget_1_3-1.3.pdf
261792 RR_KeyPersonExpanded_2_0-2.0.pdf
261792 RR_OtherProjectInfo_1_3-1.3.pdf
261792 PerformanceSite_2_0-2.0.pdf
Optional forms
261792 PlannedReport-1.0.pdf
261792 PHS398_CumulativeInclusionReport-1.0.pdf
261792 RR_SubawardBudget30_1_3-1.3.pdf
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