National Institute on Alcohol Abuse and Alcoholism Grant: Investigating Alcohol Impairment of Immune Function

This grant opportunity aims to support basic and translational research on understanding how alcohol abuse affects the immune system leading to increased susceptibility to infections and organ damage. The focus is on identifying mechanisms of immune alterations induced by alcohol, linking these changes to alcohol-related medical issues, and developing strategies to mitigate immune impairment for the purpose of reducing alcohol-induced pathology. Closing date for applications is January 7, 2015.

Opportunity ID: 131396

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	PA-12-026
Funding Opportunity Title::	Alcohol impairment of immune function, host defense and tissue homeostasis (R21)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.273 — Alcohol Research Programs
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Nov 18, 2011
Last Updated Date::
Original Closing Date for Applications::	Jan 07, 2015
Current Closing Date for Applications::	Jan 07, 2015
Archive Date::	Feb 07, 2015
Estimated Total Program Funding::
Award Ceiling::	$200,000
Award Floor::	$

Eligibility

Eligible Applicants::

City or township governments

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	Susceptibility to infection and organ damage are the two most common causes of alcohol-related morbidity and mortality. These consequences of alcohol abuse are closely associated with profound impairment of the host innate and adaptive immune systems. The mechanisms of these immune alterations and their link with alcohol-related medical problems are, in most cases, poorly understood. The goal of this FOA is to attract applications on basic and translational research: 1) to identify how alcohol alters immune function; 2) to establish functional links between immune alterations and alcohol related infections and organ damage; and 3) to develop means for mitigating immune impairment with the goal of alleviating alcohol-induced pathology.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:	93.273
Competition ID:	ADOBE-FORMS-B2
Competition Title:	ADOBE-FORMS-B2
Opportunity Package ID:	PKG00086122
Opening Date:	Jan 16, 2012
Closing Date:	Sep 24, 2013
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]