National Institute on Alcohol Abuse and Alcoholism Grant: Investigating Ethanol Metabolizing Enzymes in Health and Disease (R01)

This grant from the National Institute on Alcohol Abuse and Alcoholism supports research on the unconventional roles of ethanol metabolizing enzymes, metabolites, and cofactors in health and disease. The focus is on understanding how these pathways contribute to alcohol-induced diseases and end organ injuries, with the goal of identifying key components for diagnosis, treatment, and management of medical disorders resulting from long term alcohol consumption. Researchers are encouraged to explore innovative approaches that could lead to breakthroughs in improving disease outcomes and public health related to alcohol-induced pathologies.

Opportunity ID: 182654

Apply

General Information

Document Type::	Grants Notice
Funding Opportunity Number::	PA-12-235
Funding Opportunity Title::	Unconventional Roles of Ethanol Metabolizing Enzymes, Metabolites, and Cofactors in Health and Disease (R01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.273 — Alcohol Research Programs
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 4
Posted Date::	Jul 10, 2012
Last Updated Date::	May 01, 2014
Original Closing Date for Applications::	Jan 07, 2015
Current Closing Date for Applications::	May 01, 2014
Archive Date::	Jun 01, 2014
Estimated Total Program Funding::
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

Native American tribal organizations (other than Federally recognized tribal governments)

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	The purpose of this FOA is to provide support for integrated, innovative research on the novel and unconventional contributions of ethanol metabolizing pathways, their metabolites, cofactors, and interactions with synergizing biological pathways in the development of alcohol- induced diseases and end organ injuries. It is anticipated that this FOA will generate data that may lead to breakthroughs in our understanding of identifying key cellular and molecular components in the initiation, progression and maintenance of the diverse medical disorders caused by excessive, long term alcohol consumption. In the future this knowledge may be critical in the diagnosis, treatment and management of vulnerable patient population debilitated by the vast array of alcohol-induced pathologies and enable clinicians to improve disease outcomes and, consequently, public health.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 4	This funding opportunity is being closed and archived, and has been reissued as PA-14-198.	May 01, 2014
Synopsis 3	This funding opportunity is being closed and archived, and has been reissued as PA-14-198.
Synopsis 2	This funding opportunity is being closed and archived, and has been reissued as PA-14-072.
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:	93.273
Competition ID:	ADOBE-FORMS-B2
Competition Title:	ADOBE-FORMS-B2
Opportunity Package ID:	PKG00131310
Opening Date:	Sep 05, 2012
Closing Date:	Sep 24, 2013
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]