This grant, offered by the National Institute on Drug Abuse (NIDA), aims to support the generation of single cell datasets focusing on brain regions relevant to opioid use disorder and persistent HIV infection. The project targets to create a cellular parts list for selected brain regions, identify differences in gene expression among cell types, explore how chronic opioid exposure affects cell types for potential therapeutic targets, investigate how HIV infection influences single cells for improving HIV neurobiological consequences, and uncover potential synergies between chronic opioid exposure and HIV infection in the CNS. Closing date for application is Oct 08, 2019.
Opportunity ID: 314424
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-19-037 |
| Funding Opportunity Title: | Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: CNS Data Generation (UM1 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 01, 2019 |
| Last Updated Date: | Apr 01, 2019 |
| Original Closing Date for Applications: | Oct 08, 2019 |
| Current Closing Date for Applications: | Oct 08, 2019 |
| Archive Date: | Nov 13, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Public and State controlled institutions of higher education Private institutions of higher education City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts County governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Special district governments Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | To support generation of single cell datasets for one or more brain regions relevant to opioid use disorder and persistent HIV infection. If fully successful, this project will generate 1. A cellular parts list for selected NIDA-relevant brain regions, 2. Reveal how cell types within these brain regions differ from one another with respect to gene expression, 3. Reveal how cell types within these brain regions are altered by chronic opioid exposure providing potential novel therapeutic targets for opioid addiction, 4. Reveal how HIV infection in the CNS influences single cells, providing potential targets for improving HIV neurobiological sequelae, and 5. Uncover potential synergistic effects of chronic opioid exposure and HIV infection in the CNS. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-19-037.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | FORMS-E | PKG00249606 | Apr 08, 2019 | Oct 08, 2019 | View |
Package 1
Mandatory forms
314424 RR_SF424_2_0-2.0.pdf
314424 PHS398_CoverPageSupplement_4_0-4.0.pdf
314424 RR_OtherProjectInfo_1_4-1.4.pdf
314424 PerformanceSite_2_0-2.0.pdf
314424 RR_KeyPersonExpanded_2_0-2.0.pdf
314424 RR_Budget_1_4-1.4.pdf
314424 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
314424 RR_SubawardBudget30_1_4-1.4.pdf
314424 PHS_AssignmentRequestForm_2_0-2.0.pdf
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