The National Institutes of Health is offering this grant to support critical research aimed at improving the HIV Pre-Exposure Prophylaxis (PrEP) care continuum for people who use substances. This grant is for the purpose of addressing significant challenges in PrEP awareness, uptake, and adherence, which remain suboptimal despite PrEP’s proven efficacy in preventing HIV transmission. Projects funded through this initiative will delve into systemic and structural factors that either hinder or facilitate access to and sustained use of PrEP among this vulnerable population. The ultimate goal is to develop, implement, and rigorously evaluate effective, tailored strategies that meet the specific needs of people who use substances, thereby enhancing their engagement throughout the PrEP care continuum and ultimately reducing new HIV infections.
Opportunity ID: 357494
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-26-003 |
| Funding Opportunity Title: | Research to Address Systemic and Structural Barriers and Facilitators to Improve the HIV Pre-Exposure Prophylaxis (PrEP) Care Continuum for People Who Use Substances (R01 Clinical Trials Required) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Use and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 02, 2024 |
| Last Updated Date: | Dec 02, 2024 |
| Original Closing Date for Applications: | Mar 12, 2025 |
| Current Closing Date for Applications: | Mar 12, 2025 |
| Archive Date: | Apr 17, 2025 |
| Estimated Total Program Funding: | $500,000 |
| Award Ceiling: | $500,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Small businesses Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) State governments City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Pre-exposure prophylaxis, also known as PrEP, is a safe, highly effective medication for preventing transmission of HIV from sex or injection drug use. Despite PrEPs high efficacy and its availability for over a decade, the awareness, uptake, and adherence of PrEP, especially among people who use substances remain suboptimal. The goal of this concept is to support research to examine and address systemic and structural factors that impede or facilitate the PrEP awareness, uptake, and adherence, among people who use substances. Projects will develop, implement, and evaluate effective strategies that meet the needs of people who use substances to improve the PrEP care continuum. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-26-003.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357494 Full Announcement-RFA-DA-26-003 -> RFA-DA-26-003-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289349 | Feb 12, 2025 | Mar 12, 2025 | View |
Package 1
Mandatory forms
357494 RR_SF424_5_0-5.0.pdf
357494 PHS398_CoverPageSupplement_5_0-5.0.pdf
357494 RR_OtherProjectInfo_1_4-1.4.pdf
357494 PerformanceSite_4_0-4.0.pdf
357494 RR_KeyPersonExpanded_4_0-4.0.pdf
357494 PHS398_ResearchPlan_5_0-5.0.pdf
357494 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357494 RR_Budget_3_0-3.0.pdf
357494 RR_SubawardBudget30_3_0-3.0.pdf
357494 PHS398_ModularBudget_1_2-1.2.pdf
357494 PHS_AssignmentRequestForm_4_0-4.0.pdf
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