This grant, offered by the National Institutes of Health (NIH), is designed to invite research applications focusing on current and high-priority topics within Alzheimer’s disease (AD) and its related dementias (ADRD). The primary purpose is to stimulate innovative scientific inquiry into various facets of these neurological conditions. While this funding opportunity establishes the broad scope, specific areas of high-priority interest will be detailed in subsequent official Notices. Researchers are encouraged to prepare proposals that align with the evolving landscape of AD and ADRD research, contributing to advancements in understanding, prevention, diagnosis, and treatment. This initiative aims to foster significant breakthroughs in combating these debilitating diseases.
Opportunity ID: 357935
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-332 |
| Funding Opportunity Title: | Research on Current Topics in Alzheimer’s Disease and Its Related Dementias (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 30, 2024 |
| Last Updated Date: | Jul 03, 2025 |
| Original Closing Date for Applications: | Nov 05, 2027 |
| Current Closing Date for Applications: | Nov 05, 2027 |
| Archive Date: | Dec 11, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses County governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments State governments Independent school districts Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications proposing research on current topics in Alzheimer’s disease (AD) and its related dementias (ADRD). Further information on the high-priority topics of interest will be announced through a series of Notices published subsequent to this NOFO. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-332.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Add ALN/CFDA per NOT-DE-25-046. | Jul 03, 2025 | |
| Dec 30, 2024 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-332 |
| Funding Opportunity Title: | Research on Current Topics in Alzheimer’s Disease and Its Related Dementias (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Dec 30, 2024 |
| Last Updated Date: | Jul 03, 2025 |
| Original Closing Date for Applications: | Nov 05, 2027 |
| Current Closing Date for Applications: | Nov 05, 2027 |
| Archive Date: | Dec 11, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses County governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments State governments Independent school districts Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications proposing research on current topics in Alzheimer’s disease (AD) and its related dementias (ADRD). Further information on the high-priority topics of interest will be announced through a series of Notices published subsequent to this NOFO. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-332.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-25-332 |
| Funding Opportunity Title: | Research on Current Topics in Alzheimer’s Disease and Its Related Dementias (R01 Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.853 — Extramural Research Programs in the Neurosciences and Neurological Disorders |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 30, 2024 |
| Last Updated Date: | Dec 30, 2024 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | Nov 05, 2027 |
| Archive Date: | Dec 11, 2027 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) State governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Private institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Small businesses For profit organizations other than small businesses Special district governments Public housing authorities/Indian housing authorities City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications proposing research on current topics in Alzheimer’s disease (AD) and its related dementias (ADRD). Further information on the high-priority topics of interest will be announced through a series of Notices published subsequent to this NOFO. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/pa-files/PAR-25-332.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Related Documents
Folder 357935 Full Announcement-PAR-25-332 -> PAR-25-332-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289830 | Feb 11, 2025 | Nov 05, 2027 | View |
Package 1
Mandatory forms
357935 RR_SF424_5_0-5.0.pdf
357935 PHS398_CoverPageSupplement_5_0-5.0.pdf
357935 RR_OtherProjectInfo_1_4-1.4.pdf
357935 PerformanceSite_4_0-4.0.pdf
357935 RR_KeyPersonExpanded_4_0-4.0.pdf
357935 PHS398_ResearchPlan_5_0-5.0.pdf
357935 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357935 RR_Budget_3_0-3.0.pdf
357935 RR_SubawardBudget30_3_0-3.0.pdf
357935 PHS398_ModularBudget_1_2-1.2.pdf
357935 PHS_AssignmentRequestForm_4_0-4.0.pdf
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