National Institutes of Health: Multi-Omics for Health and Disease Grant

The National Institutes of Health is offering the Multi-Omics for Health and Disease grant to establish Omics Production Center(s) as part of a collaborative effort to advance multi-omic technologies in studying health and disease in diverse populations. The grant aims to explore multi-omics integration with phenotypic and environmental data, develop data harmonization methods, and create a multi-dimensional dataset for research. The focus is on validating and improving multi-omic approaches to identify biological changes related to health and disease. Closing date for this grant is on November 18, 2022.

Opportunity ID: 343393

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-HG-22-009
Funding Opportunity Title::	Multi-Omics for Health and Disease – ‘Omics Production Centers (U01 Clinical Trial Not Allowed)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Education
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.113 — Environmental Health
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Sep 07, 2022
Last Updated Date::	Sep 07, 2022
Original Closing Date for Applications::	Nov 18, 2022
Current Closing Date for Applications::	Nov 18, 2022
Archive Date::	Dec 24, 2022
Estimated Total Program Funding::
Award Ceiling::	$2,700,000
Award Floor::	$

Eligibility

Eligible Applicants::

City or township governments

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	The goal of this Funding Opportunity Announcement (FOA) is to establish Omics Production Center(s) (OPC(s)) that will be part of a collaborative initiative to advance the application of multi-omic technologies to study health and disease in diverse populations. Together with the Disease Study Sites (RFA-HG-22-008) and the Data Analysis and Coordination Center (RFA-HG-22-010), the Omics Production Center(s) will leverage clinical conditions where multi-omic approaches are expected to be most informative to: 1) explore the use of multi-omics, integrated with phenotypic and environmental exposure data, including social determinants of health (SDOH), to detect and assess molecular profiles associated with healthy and disease states; 2) develop generalizable data harmonization, integration, and analysis methods, as well as best practices and standards for the optimal application of multi-omics; and 3) create a multi-dimensional dataset that is available to the research community. The OPC(s) will be primarily responsible for using high high-throughput molecular assays to produce omics data from the biosamples provided by the Disease Study Sites (DSS, RFA-HG-22-008) and contributing to consortium-wide protocol development, data analysis, methods development, and the production of the multi-dimensional dataset. While this program may provide some insights into disease etiology, its primary goal is to validate and enhance generalizable multi-omic approaches to identify meaningful biological changes related to health and disease.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1		Sep 07, 2022

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	FORMS-G
Competition Title:	Use for due dates on or after January 25, 2022
Opportunity Package ID:	PKG00276676
Opening Date:	Oct 18, 2022
Closing Date:	Nov 18, 2022
Agency Contact Information::	eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V5.0] PHS 398 Cover Page Supplement [V5.0] Research And Related Other Project Information [V1.4] Project/Performance Site Location(s) [V4.0] Research and Related Senior/Key Person Profile (Expanded) [V4.0] PHS 398 Research Plan [V4.0] PHS Human Subjects and Clinical Trials Information [V3.0]
optional_forms	Research & Related Budget [V3.0] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V3.0] PHS 398 Modular Budget [V1.2] PHS Assignment Request Form [V3.0]

Assistance Listings:
Competition ID:	FORMS-H
Competition Title:	Use for due dates on or after January 25, 2023
Opportunity Package ID:	PKG00277984
Opening Date:	Nov 04, 2022
Closing Date:	Nov 18, 2022
Agency Contact Information::	eRA Service Desk Monday to Friday 7 am to 8 pm ET http://grants.nih.gov/support/
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V5.0] PHS 398 Cover Page Supplement [V5.0] Research And Related Other Project Information [V1.4] Project/Performance Site Location(s) [V4.0] Research and Related Senior/Key Person Profile (Expanded) [V4.0] PHS 398 Research Plan [V5.0] PHS Human Subjects and Clinical Trials Information [V3.0]
optional_forms	Research & Related Budget [V3.0] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V3.0] PHS 398 Modular Budget [V1.2] PHS Assignment Request Form [V3.0]