This National Institutes of Health (NIH) grant is offered to support research into the molecular genetics of drug addiction and its co-morbidities. The primary purpose of this grant is to identify and validate specific genetic markers and variations linked to addiction vulnerability and responsiveness to treatment. Projects are encouraged to utilize molecular genetic approaches, including computational and large-scale genomic studies, and to examine intermediate phenotypes. Data can be sourced from human populations or animal models, with secondary data analysis also suitable. Investigators are invited to explore complex interactions like gene-environment and pharmacogenetics, and to employ non-human models, advancing our understanding of addiction’s biological underpinnings.
Opportunity ID: 249078
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-14-025 |
| Funding Opportunity Title: | Discovering Novel Targets: The Molecular Genetics of Drug Addiction and Related Co-Morbidities (R01) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 10, 2013 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jan 07, 2017 |
| Current Closing Date for Applications: | Jan 07, 2017 |
| Archive Date: | Feb 07, 2017 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Private institutions of higher education Special district governments Independent school districts Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education State governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments For profit organizations other than small businesses County governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA encourages applications for research projects that identify and/or validate chromosomal loci and variations in genes that are associated with vulnerability to addiction and that inform the likelihood of responsiveness to treatment. Applications that propose to examine intermediate phenotypes or endophenotypes to assess the molecular genetics of drug addiction, addiction vulnerability and/or their associated co-morbidities and how they are related to drug addiction are especially encouraged. Also encouraged are genetic as well as computational and large-scale genomic approaches, which may include but are not limited to linkage, linkage disequilibrium, case-control or family-based studies, and integration of data from other databases that may supplement substance abuse genetics and genomics data. Data may be collected from the general population, special populations, recent admixed populations, and/or animal models. Secondary data analysis of data collected from the general population, special populations, recent admixed populations, and/or animal models is also appropriate for this announcement. Investigators are encouraged to include, as a component of their project and as appropriate, gene x gene interactions, gene x environment interactions, gene x environment x development interactions, pharmacogenetics, and non-human models. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-14-025.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| 93.279 | FORMS-C | Forms-C | PKG00190940 | Jan 05, 2014 | May 07, 2016 | View |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00222104 | Apr 17, 2016 | Jan 07, 2017 | View |
Package 1
Mandatory forms
249078 RR_SF424_2_0-2.0.pdf
249078 PHS398_ResearchPlan_2_0-2.0.pdf
249078 PHS398_CoverPageSupplement_2_0-2.0.pdf
249078 RR_KeyPersonExpanded_2_0-2.0.pdf
249078 RR_OtherProjectInfo_1_3-1.3.pdf
249078 PerformanceSite_2_0-2.0.pdf
Optional forms
249078 RR_SubawardBudget30_1_3-1.3.pdf
249078 PlannedReport-1.0.pdf
249078 PHS398_CumulativeInclusionReport-1.0.pdf
249078 PHS398_ModularBudget_1_2-1.2.pdf
249078 RR_Budget_1_3-1.3.pdf
Package 2
Mandatory forms
249078 RR_SF424_2_0-2.0.pdf
249078 PHS398_CoverPageSupplement_3_0-3.0.pdf
249078 RR_OtherProjectInfo_1_3-1.3.pdf
249078 PerformanceSite_2_0-2.0.pdf
249078 RR_KeyPersonExpanded_2_0-2.0.pdf
249078 PHS398_ResearchPlan_3_0-3.0.pdf
Optional forms
249078 RR_Budget_1_3-1.3.pdf
249078 RR_SubawardBudget30_1_3-1.3.pdf
249078 PHS398_ModularBudget_1_2-1.2.pdf
249078 PHS_Inclusion_Enrollment_Report-1.0.pdf
249078 PHS_AssignmentRequestForm-1.0.pdf
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