This National Institutes of Health (NIH) grant opportunity promotes fundamental research aimed at understanding the mechanisms by which vaccines against infectious agents confer long-lasting protective immunity. The initiative supports studies defining the specific immune system components and pathways crucial for vaccine durability. This grant is for researchers proposing to decipher human immune responses elicited through vaccination, primarily through the use of human cells and tissues. Animal studies are also permissible to elucidate mechanistic pathways that are challenging to investigate using human samples alone. The overarching purpose is to improve our scientific understanding of how to achieve and maintain durable vaccine-induced protection.
Opportunity ID: 343203
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-22-055 |
| Funding Opportunity Title: | Maintaining Immunity after Immunization (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy and Infectious Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 22, 2022 |
| Last Updated Date: | Aug 22, 2022 |
| Original Closing Date for Applications: | Jan 13, 2023 |
| Current Closing Date for Applications: | Jan 13, 2023 |
| Archive Date: | Feb 18, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $450,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education City or township governments For profit organizations other than small businesses County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments Private institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The goal of this Funding Opportunity Announcement (FOA) is to promote research to improve our understanding of how vaccines against infectious agents lead to durable protective immunity. This initiative will support studies that define components and mechanisms of the immune system that determine such durability. Applications must propose the use of human cells/tissues to decipher the human response elicited through vaccination. Animal studies also may be included to elucidate mechanistic pathways not easily accomplished with human samples. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-22-055.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 343203 Full Announcement-RFA-AI-22-055 -> RFA-AI-22-055-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00276485 | Dec 13, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277971 | Dec 13, 2022 | Jan 13, 2023 | View |
Package 1
Mandatory forms
343203 RR_SF424_5_0-5.0.pdf
343203 PHS398_CoverPageSupplement_5_0-5.0.pdf
343203 RR_OtherProjectInfo_1_4-1.4.pdf
343203 PerformanceSite_4_0-4.0.pdf
343203 RR_KeyPersonExpanded_4_0-4.0.pdf
343203 PHS398_ResearchPlan_4_0-4.0.pdf
343203 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343203 RR_Budget_3_0-3.0.pdf
343203 RR_SubawardBudget30_3_0-3.0.pdf
343203 PHS398_ModularBudget_1_2-1.2.pdf
343203 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
343203 RR_SF424_5_0-5.0.pdf
343203 PHS398_CoverPageSupplement_5_0-5.0.pdf
343203 RR_OtherProjectInfo_1_4-1.4.pdf
343203 PerformanceSite_4_0-4.0.pdf
343203 RR_KeyPersonExpanded_4_0-4.0.pdf
343203 PHS398_ResearchPlan_5_0-5.0.pdf
343203 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
343203 RR_Budget_3_0-3.0.pdf
343203 RR_SubawardBudget30_3_0-3.0.pdf
343203 PHS398_ModularBudget_1_2-1.2.pdf
343203 PHS_AssignmentRequestForm_3_0-3.0.pdf
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