The National Cancer Institute (NCI), National Institute on Alcohol Abuse and Alcoholism (NIAAA), and the Office of Dietary Supplements (ODS) are offering this R21 Exploratory/Developmental grant. This grant is for promoting clinical and preclinical research aimed at understanding how diet and dietary factors, including supplements, influence epigenetic processes like DNA methylation, histone modification, and noncoding RNA in cancer prevention and development. A key purpose is to encourage collaborations between nutrition and epigenetic experts. This initiative supports studying bioactive food components with cancer-preventative properties and examining crucial epigenetic events in cancer processes to establish links between epigenetics, methylation patterns, and tumor incidence/behavior.
Opportunity ID: 48481
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PA-09-235 |
| Funding Opportunity Title: | Diet, Epigenetic Events, and Cancer Prevention (R21) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.273 — Alcohol Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jul 15, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Sep 07, 2012 |
| Current Closing Date for Applications: | Sep 07, 2012 |
| Archive Date: | Oct 08, 2012 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $200,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses County governments Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses City or township governments Public and State controlled institutions of higher education Special district governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. The aim of this funding opportunity announcement (FOA), issued by the National Cancer Institute (NCI), the National Institute on Alcohol Abuse and Alcoholism (NIAAA), and the Office of Dietary Supplements (ODS), of the National Institutes of Health (NIH), is to promote clinical and preclinical research to determine how diet and dietary factors, including dietary supplements, impact DNA methylation, histone posttranslational modification, noncoding RNA, and other epigenetic processes involved in cancer prevention and development. Another important aim of this initiative is to encourage collaborations between nutrition and epigenetic experts to study bioactive food components with cancer-preventative properties and to examine key epigenetic events in cancer processes (e.g., carcinogen metabolism, cell division, differentiation, and apoptosis) in order to begin to establish linkages between epigenetics, methylation patterns, and tumor incidences/behaviors. Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with a FOA of identical scientific scope, PA-09-234, that encourages applications under the Research Project Grant (R01) mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism, numbers, quality, duration, and costs of the applications received. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PA-09-235.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| ADOBE-FORMS-B1 | Supersedes ADOBE-FORMS-B | PKG00022234 | Oct 30, 2010 | Sep 07, 2012 | View | |
| ADOBE-FORMS-A | Adobe-Forms-A | PKG00013090 | Sep 16, 2009 | Feb 20, 2010 | View | |
| ADOBE-FORMS-B | Use for submissions intended for due dates of January 25, 2010 and beyond | PKG00015341 | Dec 21, 2009 | Oct 30, 2010 | View |
Package 1
Mandatory forms
48481 RR_SF424_1_2-1.2.pdf
48481 RR_OtherProjectInfo_1_3-1.3.pdf
48481 RR_KeyPersonExpanded_1_2-1.2.pdf
48481 PerformanceSite_1_4-1.4.pdf
48481 PHS398_ResearchPlan_1_3-1.3.pdf
48481 PHS398_CoverPageSupplement_1_4-1.4.pdf
48481 PHS398_Checklist_1_3-1.3.pdf
Optional forms
48481 RR_Budget-1.1.pdf
48481 RR_SubawardBudget-1.2.pdf
48481 PHS_CoverLetter_1_2-1.2.pdf
48481 PHS398_ModularBudget-1.1.pdf
Package 2
Mandatory forms
48481 RR_SF424-1.1.pdf
48481 RR_KeyPersonExpanded-1.1.pdf
48481 RR_OtherProjectInfo-1.1.pdf
48481 RR_PerformanceSite-1.1.pdf
48481 PHS398_CoverPageSupplement-1.1.pdf
48481 PHS398_ResearchPlan-1.1.pdf
48481 PHS398_Checklist-1.1.pdf
Optional forms
48481 PHS398_CoverLetter-1.1.pdf
48481 PHS398_ModularBudget-1.1.pdf
48481 RR_Budget-1.1.pdf
48481 RR_SubawardBudget-1.2.pdf
Package 3
Mandatory forms
48481 RR_SF424_1_2-1.2.pdf
48481 PerformanceSite_1_3-1.3.pdf
48481 RR_OtherProjectInfo_1_2-1.2.pdf
48481 RR_KeyPersonExpanded_1_2-1.2.pdf
48481 PHS398_CoverPageSupplement_1_4-1.4.pdf
48481 PHS398_ResearchPlan_1_3-1.3.pdf
48481 PHS398_Checklist_1_3-1.3.pdf
Optional forms
48481 PHS_CoverLetter_1_2-1.2.pdf
48481 PHS398_ModularBudget-1.1.pdf
48481 RR_Budget-1.1.pdf
48481 RR_SubawardBudget-1.2.pdf
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