National Institutes of Health: Targeting Persistent HIV Reservoirs (TaPHIR) Grant

This grant aims to develop innovative tools and strategies to cure HIV infection by identifying and eliminating reservoirs of virus that persist in infected individuals. The challenge lies in targeting latently infected cells that do not express HIV proteins and are present at low frequencies during treatment. The grant seeks novel approaches to monitor and target these reservoir cells, facilitating the testing of strategies to cure HIV infection in vivo. Closing date for application is April 25, 2014.

Opportunity ID: 144893

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	PAR-12-109
Funding Opportunity Title::	Targeting Persistent HIV Reservoirs (TaPHIR) (R21/R33)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.242 — Mental Health Research Grants
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Feb 17, 2012
Last Updated Date::
Original Closing Date for Applications::	Apr 25, 2014
Current Closing Date for Applications::	Apr 25, 2014
Archive Date::	May 26, 2014
Estimated Total Program Funding::
Award Ceiling::	$
Award Floor::	$

Eligibility

Eligible Applicants::

County governments

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	The purpose of this FOA is to stimulate the development of innovative tools and strategies for curing HIV infection. HIV establishes latent infection in long-lived cells that form a reservoir of virus that persists in infected individuals even after years of treatment with highly active antiretroviral therapy (HAART). Curing HIV infection requires innovative strategies to identify and eliminate these reservoir cells. The task is especially difficult given the lack of HIV protein expression during latency and the low frequency of latently infected cells during treatment. Novel approaches are therefore sought to efficiently monitor and specifically target reservoirs of latently infected cells to facilitate the testing of strategies to cure HIV infection in vivo.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package Status

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	ADOBE-FORMS-B2
Competition Title:	ADOBE-FORMS-B2
Opportunity Package ID:	PKG00098290
Opening Date:	Feb 25, 2012
Closing Date:	Sep 24, 2013
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] Research & Related Budget [V1.1] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS Cover Letter [V1.2]