This grant is for supporting early-stage research focused on identifying new druggable targets for pain, opioid use disorder, and/or overdose. Offered by NCATS, this funding opportunity responds to the declared public health emergency of the opioid crisis. It is a key component of the NIH Helping to End Addiction Long Term (HEAL) initiative. The primary purpose is to accelerate the development of novel medications. These medications aim to treat all facets of the opioid addiction cycle, including the progression to chronic use, withdrawal symptoms, craving, relapse, and overdose. The research should specifically target the understudied druggable proteome.
Opportunity ID: 347534
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-TR-23-010 |
| Funding Opportunity Title: | Emergency Awards: HEAL Initiative-Early-Stage Discovery of New Pain and Opioid Use Disorder Targets Within the Understudied Druggable Proteome (R21 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health Income Security and Social Services |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Apr 14, 2023 |
| Last Updated Date: | Apr 14, 2023 |
| Original Closing Date for Applications: | May 22, 2023 |
| Current Closing Date for Applications: | May 22, 2023 |
| Archive Date: | Jun 27, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses For profit organizations other than small businesses Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Private institutions of higher education Special district governments Independent school districts Public housing authorities/Indian housing authorities Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education State governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | NCATS is issuing this FOA in response to the declared public health emergency issued by the Secretary, HHS. Please see Determination that a Public Health Emergency Exists Nationwide as the Result of the Opioid Crisis as renewed in Renewal of the Determination that a Public Health Emergency Exists Nationwide as the Result of the Continued Consequences of the Opioid Crisis.The purpose of this funding opportunity announcement (FOA) is to support early-stage research projects focusing on the identification of new druggable targets for pain, opioid use disorder and/or overdose within the understudied druggable proteome. This FOA is part of the NIH Helping to End Addiction Long Term (HEAL) initiative to accelerate the development of novel medications to treat all aspects of the opioid addiction cycle, including progression to chronic use, withdrawal symptoms, craving, relapse, and overdose. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-TR-23-010.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00281176 | Apr 21, 2023 | May 22, 2023 | View |
Package 1
Mandatory forms
347534 RR_SF424_5_0-5.0.pdf
347534 PHS398_CoverPageSupplement_5_0-5.0.pdf
347534 RR_OtherProjectInfo_1_4-1.4.pdf
347534 PerformanceSite_4_0-4.0.pdf
347534 RR_KeyPersonExpanded_4_0-4.0.pdf
347534 PHS398_ResearchPlan_5_0-5.0.pdf
347534 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
347534 RR_Budget_3_0-3.0.pdf
347534 RR_SubawardBudget30_3_0-3.0.pdf
347534 PHS398_ModularBudget_1_2-1.2.pdf
347534 PHS_AssignmentRequestForm_3_0-3.0.pdf
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