This grant, offered by the National Cancer Institute (NCI), is for supporting research into the use of microorganisms and their natural products for cancer imaging, therapeutics, and diagnostics. Projects should investigate the complex interactions between microbes, tumors, and the immune system. Applicants can propose using microorganisms as anti-tumor agents, activators of anti-tumor immunity, or delivery vehicles, complementing existing cancer treatment approaches. This funding opportunity supports basic mechanistic and preclinical studies using cell culture and animal models, encouraging a focus on both microbial and tumor aspects of these interactions, including applications for oral cancer.
Opportunity ID: 338200
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-085 |
| Funding Opportunity Title: | Microbial-based Cancer Imaging and Therapy – Bugs as Drugs (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Feb 18, 2022 |
| Last Updated Date: | Nov 08, 2024 |
| Original Closing Date for Applications: | May 07, 2025 |
| Current Closing Date for Applications: | Nov 08, 2024 |
| Archive Date: | Dec 08, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments For profit organizations other than small businesses Private institutions of higher education County governments City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy. (link to OCCAM) |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-085.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| updated close date | Nov 08, 2024 | |
| Feb 18, 2022 |
DISPLAYING: Synopsis 2
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-085 |
| Funding Opportunity Title: | Microbial-based Cancer Imaging and Therapy – Bugs as Drugs (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 2 |
| Posted Date: | Feb 18, 2022 |
| Last Updated Date: | Nov 08, 2024 |
| Original Closing Date for Applications: | May 07, 2025 |
| Current Closing Date for Applications: | Nov 08, 2024 |
| Archive Date: | Dec 08, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments For profit organizations other than small businesses Private institutions of higher education County governments City or township governments Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: |
This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy. (link to OCCAM) |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-085.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
DISPLAYING: Synopsis 1
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-22-085 |
| Funding Opportunity Title: | Microbial-based Cancer Imaging and Therapy – Bugs as Drugs (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.121 — Oral Diseases and Disorders Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 18, 2022 |
| Last Updated Date: | Feb 18, 2022 |
| Original Closing Date for Applications: | – |
| Current Closing Date for Applications: | May 07, 2025 |
| Archive Date: | Jun 12, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | State governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Independent school districts County governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities City or township governments Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Special district governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits grant applications proposing to utilize bacteria, archaebacteria, bacteriophages, or other non-oncolytic viruses and their natural products to study the underlying mechanisms of the complex interactions between microorganisms, tumors, and the immune system, and to explore their clinical potential for cancer imaging, therapeutics or diagnostics. Projects can focus on using microorganisms as anti-tumor agents, as activators of anti-tumor immunity, or as delivery vehicles for treatment, diagnosis, or imaging, complementing or synergizing with existing tools and approaches. This FOA will support basic mechanistic and preclinical studies in cell culture and animal models. Applicants are encouraged to address both the microbial and tumor aspects of microbial tumor interactions relevant to microbial-based cancer therapy (including therapies for oral cancer), tumor imaging, tumor detection, or diagnosis. This funding opportunity is part of broader NCI-sponsored research on microbial-based cancer therapy. (link to OCCAM) |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-22-085.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00272144 | May 05, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or before January 24, 2025 | PKG00277796 | Nov 01, 2022 | Jan 24, 2025 | View | |
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00288562 | Nov 07, 2024 | Nov 09, 2024 | View |
Package 1
Mandatory forms
338200 RR_SF424_5_0-5.0.pdf
338200 PHS398_CoverPageSupplement_5_0-5.0.pdf
338200 RR_OtherProjectInfo_1_4-1.4.pdf
338200 PerformanceSite_4_0-4.0.pdf
338200 RR_KeyPersonExpanded_4_0-4.0.pdf
338200 PHS398_ResearchPlan_4_0-4.0.pdf
338200 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338200 RR_Budget_3_0-3.0.pdf
338200 RR_SubawardBudget30_3_0-3.0.pdf
338200 PHS398_ModularBudget_1_2-1.2.pdf
338200 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
338200 RR_SF424_5_0-5.0.pdf
338200 PHS398_CoverPageSupplement_5_0-5.0.pdf
338200 RR_OtherProjectInfo_1_4-1.4.pdf
338200 PerformanceSite_4_0-4.0.pdf
338200 RR_KeyPersonExpanded_4_0-4.0.pdf
338200 PHS398_ResearchPlan_5_0-5.0.pdf
338200 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338200 RR_Budget_3_0-3.0.pdf
338200 RR_SubawardBudget30_3_0-3.0.pdf
338200 PHS398_ModularBudget_1_2-1.2.pdf
338200 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
338200 RR_SF424_5_0-5.0.pdf
338200 PHS398_CoverPageSupplement_5_0-5.0.pdf
338200 RR_OtherProjectInfo_1_4-1.4.pdf
338200 PerformanceSite_4_0-4.0.pdf
338200 RR_KeyPersonExpanded_4_0-4.0.pdf
338200 PHS398_ResearchPlan_5_0-5.0.pdf
338200 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
338200 RR_Budget_3_0-3.0.pdf
338200 RR_SubawardBudget30_3_0-3.0.pdf
338200 PHS398_ModularBudget_1_2-1.2.pdf
338200 PHS_AssignmentRequestForm_4_0-4.0.pdf
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