This grant, offered by the National Cancer Institute (NCI), is for advancing cancer etiology and early detection biomarker research. It requires utilizing the NCI-sponsored PLCO (Prostate, Lung, Colorectal, and Ovarian Cancer) Screening Trial Biorepository. This resource provides high-quality, prospectively collected, pre-diagnostic blood samples, buccal cells, and extensive demographic/clinical data. The funding supports biochemical and genetic analyses of cancer risk, plus discovery and validation of early detection biomarkers. Proposed projects must use PLCO biospecimens to qualify; those not involving these resources will not be supported.
Opportunity ID: 335602
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-21-330 |
| Funding Opportunity Title: | Utilizing the PLCO Biospecimens Resource to Bridge Gaps in Cancer Etiology and Early Detection Research (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.393 — Cancer Cause and Prevention Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Sep 08, 2021 |
| Last Updated Date: | Sep 08, 2021 |
| Original Closing Date for Applications: | Oct 11, 2024 |
| Current Closing Date for Applications: | Oct 11, 2024 |
| Archive Date: | Nov 16, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts State governments Private institutions of higher education City or township governments For profit organizations other than small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) Small businesses Special district governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) encourages the submission of applications that propose to advance research in cancer etiology and early detection biomarkers, utilizing the advantages of the unique biorepository resources of the NCI-sponsored Prostate, Lung, Colorectal, and Ovarian Cancer (PLCO) Screening Trial. The PLCO Biorepository offers high-quality, prospectively collected, serial pre-diagnostic blood samples from the PLCO screened arm participants, and a onetime collection of buccal cells from the control arm participants. Available data associated with the biospecimens includes demographic, diet, lifestyle, smoking, screening results, and clinical data. This FOA supports a wide range of cancer research including, but not limited to, biochemical and genetic analyses of cancer risk, as well as discovery and validation of early detection biomarkers. The proposed research project must involve use of PLCO biospecimens; additionally, it should also take advantage of the unique characteristics of the PLCO biospecimens. Research projects that do not involve the use of PLCO biospecimens will not be supported under this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-21-330.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
OERWebmaster03@od.nih.gov Email:OERWebmaster03@od.nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 335602 Full Announcement-PAR-21-330 -> PAR-21-330-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster OERWebmaster03@od.nih.gov Email: OERWebmaster03@od.nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00268858 | Jan 11, 2022 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or before January 24, 2023 | PKG00270423 | Jan 11, 2022 | Jan 24, 2023 | View | |
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00277950 | Nov 04, 2022 | Oct 11, 2024 | View |
Package 1
Mandatory forms
335602 RR_SF424_2_0-2.0.pdf
335602 PHS398_CoverPageSupplement_5_0-5.0.pdf
335602 RR_OtherProjectInfo_1_4-1.4.pdf
335602 PerformanceSite_2_0-2.0.pdf
335602 RR_KeyPersonExpanded_2_0-2.0.pdf
335602 PHS398_ResearchPlan_4_0-4.0.pdf
335602 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
335602 RR_Budget_1_4-1.4.pdf
335602 RR_SubawardBudget30_1_4-1.4.pdf
335602 PHS398_ModularBudget_1_2-1.2.pdf
335602 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
335602 RR_SF424_5_0-5.0.pdf
335602 PHS398_CoverPageSupplement_5_0-5.0.pdf
335602 RR_OtherProjectInfo_1_4-1.4.pdf
335602 PerformanceSite_4_0-4.0.pdf
335602 RR_KeyPersonExpanded_4_0-4.0.pdf
335602 PHS398_ResearchPlan_4_0-4.0.pdf
335602 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335602 RR_Budget_3_0-3.0.pdf
335602 RR_SubawardBudget30_3_0-3.0.pdf
335602 PHS398_ModularBudget_1_2-1.2.pdf
335602 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
335602 RR_SF424_5_0-5.0.pdf
335602 PHS398_CoverPageSupplement_5_0-5.0.pdf
335602 RR_OtherProjectInfo_1_4-1.4.pdf
335602 PerformanceSite_4_0-4.0.pdf
335602 RR_KeyPersonExpanded_4_0-4.0.pdf
335602 PHS398_ResearchPlan_5_0-5.0.pdf
335602 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
335602 RR_Budget_3_0-3.0.pdf
335602 RR_SubawardBudget30_3_0-3.0.pdf
335602 PHS398_ModularBudget_1_2-1.2.pdf
335602 PHS_AssignmentRequestForm_3_0-3.0.pdf
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