The Neuroscience Department is offering a grant to develop in vivo neurophysiological and behavioral assays in animals for early screening of treatment development. These measures will act as surrogate markers of neural processes related to mental illnesses, enhancing preclinical data value and therapeutic development pipeline. Applicants will optimize and evaluate assays based on systems neurobiology and clinical neuroscience knowledge, aiming to assess the impact of therapeutic targets on neurobiological mechanisms of clinical relevance. Deadline for applications is Sep 07, 2022.
Opportunity ID: 316477
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-19-289 |
| Funding Opportunity Title: | Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.242 — Mental Health Research Grants |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | May 29, 2019 |
| Last Updated Date: | May 29, 2019 |
| Original Closing Date for Applications: | Sep 07, 2022 |
| Current Closing Date for Applications: | Sep 07, 2022 |
| Archive Date: | Oct 13, 2022 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Independent school districts For profit organizations other than small businesses Public and State controlled institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Private institutions of higher education Small businesses Others (see text field entitled “Additional Information on Eligibility” for clarification) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments City or township governments Special district governments Native American tribal organizations (other than Federally recognized tribal governments) |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The overall goal of this Funding Opportunity Announcement (FOA) is to identify, in animals, in vivo neurophysiological and behavioral measures for use as assays in the early screening phase of treatment development. The FOA will support efforts to optimize and evaluate measures of neurophysiological and behavioral processes that may serve as surrogate markers of neural processes of clinical interest based on available knowledge of the neurobiology of mental illnesses. The screening assays thus developed from this FOA are expected to build upon systems neurobiology and clinical neuroscience to enhance the scientific value of preclinical animal data contributing to a therapeutic development pipeline by assessing the impact of therapeutic targets and treatment candidates on neurobiological mechanisms of clinical relevance to mental illnesses. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-19-289.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 316477 Full Announcement-PAR-19-289 -> PAR-19-289-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Use for due dates on or before May 24, 2020 | PKG00251441 | Sep 05, 2019 | May 24, 2020 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00259339 | Sep 05, 2019 | Jan 24, 2022 | View | |
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00269718 | Oct 28, 2021 | Sep 07, 2022 | View |
Package 1
Mandatory forms
316477 RR_SF424_2_0-2.0.pdf
316477 PHS398_CoverPageSupplement_4_0-4.0.pdf
316477 RR_OtherProjectInfo_1_4-1.4.pdf
316477 PerformanceSite_2_0-2.0.pdf
316477 RR_KeyPersonExpanded_2_0-2.0.pdf
316477 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
316477 RR_Budget_1_4-1.4.pdf
316477 RR_SubawardBudget30_1_4-1.4.pdf
316477 PHS398_ModularBudget_1_2-1.2.pdf
316477 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
316477 RR_SF424_2_0-2.0.pdf
316477 PHS398_CoverPageSupplement_5_0-5.0.pdf
316477 RR_OtherProjectInfo_1_4-1.4.pdf
316477 PerformanceSite_2_0-2.0.pdf
316477 RR_KeyPersonExpanded_2_0-2.0.pdf
316477 PHS398_ResearchPlan_4_0-4.0.pdf
316477 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
316477 RR_Budget_1_4-1.4.pdf
316477 RR_SubawardBudget30_1_4-1.4.pdf
316477 PHS398_ModularBudget_1_2-1.2.pdf
316477 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 3
Mandatory forms
316477 RR_SF424_5_0-5.0.pdf
316477 PHS398_CoverPageSupplement_5_0-5.0.pdf
316477 RR_OtherProjectInfo_1_4-1.4.pdf
316477 PerformanceSite_4_0-4.0.pdf
316477 RR_KeyPersonExpanded_4_0-4.0.pdf
316477 PHS398_ResearchPlan_4_0-4.0.pdf
316477 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
316477 RR_Budget_3_0-3.0.pdf
316477 RR_SubawardBudget30_3_0-3.0.pdf
316477 PHS398_ModularBudget_1_2-1.2.pdf
316477 PHS_AssignmentRequestForm_3_0-3.0.pdf
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