This grant from the National Human Genome Research Institute (NHGRI) is for developing informatics tools crucial for leveraging the improved human pangenome reference. It offers multiple awards for tools addressing common use cases relevant to broad genomics sectors, including clinical, population, and functional genomics. Proposals should focus on innovative solutions for tasks such as selecting optimal subsets of linear genomes or paths for samples, visualizing complex genetic variation, and accurately annotating regulatory elements and disease associations. The initiative seeks to significantly enhance the genomics community’s capacity to utilize the advanced pangenome reference effectively.
Opportunity ID: 357569
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-HG-25-007 |
| Funding Opportunity Title: | Informatics Tools for the Pangenome (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.172 — Human Genome Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 06, 2024 |
| Last Updated Date: | Dec 06, 2024 |
| Original Closing Date for Applications: | Mar 03, 2025 |
| Current Closing Date for Applications: | Mar 03, 2025 |
| Archive Date: | Apr 08, 2025 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $400,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses State governments Private institutions of higher education Special district governments Small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts County governments City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Human Genome Research Institute (NHGRI) will renew the Human Genome Reference Program (HGRP). This Informatics Tools for the Pangenome NOFO will provide multiple awards to develop informatics tools that enable uptake and use of the improved pangenome reference. Emphasis will be on tools for common use cases that are relevant to different broad sectors of the genomics community, e.g., clinical, population, and functional genomics. Possible examples include selecting the best subset of linear genomes or paths along the graph for a given set of samples, visualizing complex variation, and annotating regulatory elements and disease associations. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-HG-25-007.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 357569 Full Announcement-RFA-HG-25-007 -> RFA-HG-25-007-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-I | Use for due dates on or after January 25, 2025 | PKG00289490 | Feb 03, 2025 | Mar 03, 2025 | View |
Package 1
Mandatory forms
357569 RR_SF424_5_0-5.0.pdf
357569 PHS398_CoverPageSupplement_5_0-5.0.pdf
357569 RR_OtherProjectInfo_1_4-1.4.pdf
357569 PerformanceSite_4_0-4.0.pdf
357569 RR_KeyPersonExpanded_4_0-4.0.pdf
357569 PHS398_ResearchPlan_5_0-5.0.pdf
357569 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
357569 RR_Budget_3_0-3.0.pdf
357569 RR_SubawardBudget30_3_0-3.0.pdf
357569 PHS398_ModularBudget_1_2-1.2.pdf
357569 PHS_AssignmentRequestForm_4_0-4.0.pdf
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