NIAID and NIA Grant: Immunity in the Elderly Research (R01)

NIAID and NIA are offering a grant to support research focused on understanding the immune mechanisms related to protective immunity in the elderly against emerging and re-emerging infections. The grant aims to investigate how aging affects immune responses, leading to severe infections and reduced vaccine efficacy. This funding opportunity emphasizes human studies to examine immune changes in older individuals, while allowing for some animal research to explore mechanisms not feasible in human subjects. Applications should address the development, maintenance, and induction of immunity in the elderly population. Closing date for submissions is February 20, 2013.

Opportunity ID: 202794

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General Information

Document Type::	Grants Notice
Funding Opportunity Number::	RFA-AI-12-038
Funding Opportunity Title::	Immunity in the Elderly (R01)
Opportunity Category::	Discretionary
Opportunity Category Explanation::
Funding Instrument Type::
Category of Funding Activity::	Health
Category Explanation::
Expected Number of Awards::
Assistance Listings Number(s)::	93.855 — Allergy, Immunology and Transplantation Research
Cost Sharing or Matching Requirement::	No
Version::	Synopsis 1
Posted Date::	Sep 28, 2012
Last Updated Date::
Original Closing Date for Applications::	Feb 20, 2013
Current Closing Date for Applications::	Feb 20, 2013
Archive Date::	Mar 23, 2013
Estimated Total Program Funding::
Award Ceiling::	$300,000
Award Floor::	$

Eligibility

Eligible Applicants::

Special district governments

Additional Information on Eligibility::

Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Additional Information

Agency Name::	National Institutes of Health
Description::	The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Aging (NIA) invite applications to define the mechanisms for induction, development, and maintenance of protective immunity in the elderly in response to infections with or vaccinations against NIAID Emerging and Re-emerging Infectious Diseases (http://www.niaid.nih.gov/topics/emerging/Pages/list.aspx). The goal of this FOA is to develop a better understanding of the immune mechanisms involved during the aging process that contribute to impaired immune responses resulting in severe infections and dampened responses to vaccines in this population. This FOA requires human studies, to gain insights into immune changes in elderly individuals. Thus, at least one aim of the project must focus fully on human studies; appropriately justified animal work may be included in additional aims to conduct mechanistic studies that are not possible in humans.
Link to Additional Information::
Grantor Contact Information::	If you have difficulty accessing the full announcement electronically, please contact:

Version History

Version	Modification Description	Updated Date
Synopsis 1

Package

Below are CLOSED Opportunity Package(s) no longer available for this Funding Opportunity:

Package No: 1

Assistance Listings:
Competition ID:	ADOBE-FORMS-B2
Competition Title:	Adobe-Forms-B2
Opportunity Package ID:	PKG00148271
Opening Date:	Jan 18, 2013
Closing Date:	Feb 20, 2013
Agency Contact Information::	Grants Info
Who Can Apply::	Organization Applicants
mendatory_forms	SF424 (R & R) [V1.2] Project/Performance Site Location(s) [V1.4] Research And Related Other Project Information [V1.3] Research And Related Senior/Key Person Profile (Expanded) [V1.2] PHS 398 Cover Page Supplement [V1.4] PHS 398 Research Plan [V1.3] PHS 398 Checklist [V1.3] R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]
optional_forms	R & R Subaward Budget Attachment(s) Form 5 YR 30 ATT [V1.2] PHS 398 Modular Budget [V1.2] Research & Related Budget [V1.1] PHS Cover Letter [V1.2]