The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) are offering a grant to support participation in the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG) program, specifically focusing on islet and kidney transplantation models. This grant is for a multi-center, cooperative research effort on nonhuman primate models of transplantation. The primary goals are to evaluate the preclinical safety and efficacy of existing and new immune tolerance induction regimens, and to elucidate the underlying mechanisms of tolerance. The long-range aim of this program is to develop and assess tolerance induction strategies that will improve long-term graft survival in clinical transplantation settings. This initiative provides support for research into NHP islet and kidney transplant tolerance.
Opportunity ID: 115175
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-11-040 |
| Funding Opportunity Title: | Nonhuman Primate Islet/Kidney Transplantation Tolerance (U19) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 17, 2011 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 14, 2011 |
| Current Closing Date for Applications: | Dec 14, 2011 |
| Archive Date: | Jan 14, 2012 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Private institutions of higher education State governments Native American tribal governments (Federally recognized) Small businesses Public housing authorities/Indian housing authorities Independent school districts Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) County governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invite new or renewal applications from single institutions and consortia of institutions to participate in the islet and kidney models portion of the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG) program. The NHPCSG is a multi-center, cooperative program for research on nonhuman primate (NHP) models of kidney, islet, heart, and lung transplantation. The goals of the NHPCSG are to evaluate the preclinical safety and efficacy of existing and newly developed immune tolerance induction regimens and to elucidate the underlying mechanisms of the induction, maintenance, and/or loss of tolerance in these models. The long-range goal of this program is to develop and evaluate tolerance induction regimens that will result in enhanced long-term graft survival in clinical transplantation. The purpose of this FOA is to provide support for the NHP islet and kidney transplantation models portion of the NHPCSG program. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-11-040.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
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