This grant offered by the National Institute of Allergy and Infectious Diseases (NIAID) and National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) supports research on immune tolerance induction regimens in nonhuman primate models of kidney and islet transplantation. The goal is to enhance long-term graft survival in clinical transplantation by evaluating preclinical safety and efficacy of tolerance induction regimens and understanding the underlying mechanisms of tolerance induction, maintenance, and loss. Applications from single institutions and consortia are invited to participate in the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG) program focusing on islet and kidney transplantation models.
Opportunity ID: 115175
General Information
| Document Type:: | Grants Notice |
| Funding Opportunity Number:: | RFA-AI-11-040 |
| Funding Opportunity Title:: | Nonhuman Primate Islet/Kidney Transplantation Tolerance (U19) |
| Opportunity Category:: | Discretionary |
| Opportunity Category Explanation:: | |
| Funding Instrument Type:: | |
| Category of Funding Activity:: | Food and Nutrition |
| Category Explanation:: | |
| Expected Number of Awards:: | |
| Assistance Listings Number(s):: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement:: | No |
| Version:: | Synopsis 1 |
| Posted Date:: | Aug 17, 2011 |
| Last Updated Date:: | |
| Original Closing Date for Applications:: | Dec 14, 2011 |
| Current Closing Date for Applications:: | Dec 14, 2011 |
| Archive Date:: | Jan 14, 2012 |
| Estimated Total Program Funding:: | |
| Award Ceiling:: | $ |
| Award Floor:: | $ |
Eligibility
| Eligible Applicants:: | Others (see text field entitled “Additional Information on Eligibility” for clarification) |
| Additional Information on Eligibility:: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name:: | National Institutes of Health |
| Description:: | The National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invite new or renewal applications from single institutions and consortia of institutions to participate in the islet and kidney models portion of the Nonhuman Primate Transplantation Tolerance Cooperative Study Group (NHPCSG) program. The NHPCSG is a multi-center, cooperative program for research on nonhuman primate (NHP) models of kidney, islet, heart, and lung transplantation. The goals of the NHPCSG are to evaluate the preclinical safety and efficacy of existing and newly developed immune tolerance induction regimens and to elucidate the underlying mechanisms of the induction, maintenance, and/or loss of tolerance in these models. The long-range goal of this program is to develop and evaluate tolerance induction regimens that will result in enhanced long-term graft survival in clinical transplantation. The purpose of this FOA is to provide support for the NHP islet and kidney transplantation models portion of the NHPCSG program. |
| Link to Additional Information:: | |
| Grantor Contact Information:: | If you have difficulty accessing the full announcement electronically, please contact: |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
| Synopsis 1 |
Package Status
Package No: 1