This grant is designed to fund multidisciplinary research focused on defining the basic immune mechanisms required to elicit broadly cross-reactive neutralizing antibody responses against HIV-1 in uninfected individuals. It specifically supports innovative studies aimed at identifying new HIV-1 envelope immunogens and immunization strategies capable of inducing these protective antibodies. Furthermore, the program fosters fundamental B cell immunology research to enhance understanding of the immunological mechanisms involved in the induction and regulation of these broad HIV-1 neutralizing antibody responses. Applicants must provide preliminary data and demonstrate expertise in basic immunology and the HIV-1 virus. This multi-project cooperative agreement promotes partnership and communication among award recipients. Importantly, clinical trials are not supported by this program.
Opportunity ID: 47970
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AI-09-022 |
| Funding Opportunity Title: | B Cell Immunology Partnership Program For HIV-1 Vaccine Discovery (U19) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.855 — Allergy, Immunology and Transplantation Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 16, 2009 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Dec 04, 2009 |
| Current Closing Date for Applications: | Dec 04, 2009 |
| Archive Date: | Jan 04, 2010 |
| Estimated Total Program Funding: | $3,000,000 |
| Award Ceiling: | $1,000,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities City or township governments Native American tribal governments (Federally recognized) Others (see text field entitled “Additional Information on Eligibility” for clarification) For profit organizations other than small businesses State governments Small businesses Special district governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | Purpose. This Funding Opportunity Announcement (FOA) issued by the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, (NIH) solicits grant applications from institutions/organizations that propose multidisciplinary research to define the basic immune mechanisms by which a broadly cross-reactive neutralizing antibody response can be elicited in uninfected individuals to protect against infection by a broad range of HIV-1 strains. Specifically, this FOA will support innovative studies to identify new HIV-1 envelope immunogens and immunization strategies for induction of broadly cross-reactive neutralizing antibody, and basic B cell immunology research designed to increase fundamental knowledge of the immunological mechanisms involved in the induction and regulation of immune responses leading to an HIV-1 broadly cross-reactive neutralizing antibody response. Preliminary data are required, and expertise in basic immunology and the HIV-1 virus should be evident. This multi-project cooperative agreement grant program will support a partnership to communicate ideas and progress among recipients of U19 awards as well as recipients of previous U01 awards issued under B Cell Immunology for Protective HIV-1 Vaccines (RFAAI-07-014). Clinical trials will not be supported by this FOA. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-09-022.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
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