NIAMS is offering a grant to develop innovative 3-dimensional in vitro human musculoskeletal and skin tissue models that align with the NIAMS mission. These models aim to serve as alternatives to animal testing, facilitating the study of human tissue physiology and disease pathophysiology for improved therapies. Projects should focus on engineering new in vitro models or technologies. Only applications using human cells in 3-D culture relevant to NIAMS mission areas will be considered. Non-responsive projects will not undergo review. Closing date for submissions is October 18, 2016.
Opportunity ID: 281045
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-AR-17-005 |
| Funding Opportunity Title: | Building Complex 3-Dimensional in Vitro Human Musculoskeletal and Skin Tissue Models (R43) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.846 — Arthritis, Musculoskeletal and Skin Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jan 19, 2016 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Oct 18, 2016 |
| Current Closing Date for Applications: | Oct 18, 2016 |
| Archive Date: | Nov 18, 2016 |
| Estimated Total Program Funding: | $1,500,000 |
| Award Ceiling: | $225,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, may be allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Funding Opportunity Announcement (FOA) solicits Phase I R43 SBIR grant applications from small businesses to develop novel complex 3-dimensional (3-D) in vitro human musculoskeletal and skin tissue models that fit into the NIAMS mission (http://www.niams.nih.gov/About_Us/Mission_and_Purpose/mission.asp). These engineered 3-D human tissue or organ models would provide alternatives to animal models of diseases and animal testing, and enable the study of human tissue physiology and disease pathophysiology in vitro and ultimately lead to better therapies that prevent or cure diseases. Applicants may propose to engineer novel in vitro models and/or develop novel technologies to meet some of the specific challenges in building these models. All applications need to use human cells in the context of in vitro 3-D culture, and must be immediately relevant to NIAMS mission areas. This FOA is not intended to support research using non-human cells or animals. Non-responsive applications will not be reviewed |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-AR-17-005.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-C | FORMS-C | PKG00220547 | Feb 03, 2016 | Feb 04, 2016 | View | |
| FORMS-D | Use for due dates on or after May 25, 2016 | PKG00221614 | Sep 18, 2016 | Oct 18, 2016 | View |
Package 1
Mandatory forms
281045 RR_SF424_2_0-2.0.pdf
281045 PHS398_ResearchPlan_2_0-2.0.pdf
281045 SBIR_STTR_Information_1_1-1.1.pdf
281045 RR_KeyPersonExpanded_2_0-2.0.pdf
281045 RR_OtherProjectInfo_1_3-1.3.pdf
281045 RR_Budget_1_3-1.3.pdf
281045 PerformanceSite_2_0-2.0.pdf
281045 PHS398_CoverPageSupplement_2_0-2.0.pdf
Optional forms
281045 RR_SubawardBudget30_1_3-1.3.pdf
281045 PlannedReport-1.0.pdf
281045 PHS398_CumulativeInclusionReport-1.0.pdf
Package 2
Mandatory forms
281045 RR_SF424_2_0-2.0.pdf
281045 PHS398_CoverPageSupplement_3_0-3.0.pdf
281045 RR_OtherProjectInfo_1_3-1.3.pdf
281045 PerformanceSite_2_0-2.0.pdf
281045 RR_KeyPersonExpanded_2_0-2.0.pdf
281045 RR_Budget_1_3-1.3.pdf
281045 PHS398_ResearchPlan_3_0-3.0.pdf
281045 SBIR_STTR_Information_1_1-1.1.pdf
Optional forms
281045 RR_SubawardBudget30_1_3-1.3.pdf
281045 PHS_Inclusion_Enrollment_Report-1.0.pdf
281045 PHS_AssignmentRequestForm-1.0.pdf
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