The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) offers the Research Innovation for Scientific Knowledge (RISK) grant for Musculoskeletal Diseases. This grant supports unconventional and innovative research projects focused on understanding disease mechanisms, developing diagnostics, therapeutic agents, or preventive interventions. While encouraging projects considered risky, premature, or controversial, the grant does not fund clinical trials. The X02 pre-application is the initial step for potential applicants, leading to the R61/R33 application process. Projects should align with NIAMS’ mission to advance knowledge in musculoskeletal diseases and address specific areas within the field. Deadline for submission is on July 3, 2019.
Opportunity ID: 308146
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | PAR-18-900 |
| Funding Opportunity Title: | Pre-Application: Research Innovation for Scientific Knowledge (RISK) for Musculoskeletal Diseases (X02 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.846 — Arthritis, Musculoskeletal and Skin Diseases Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 10, 2018 |
| Last Updated Date: | – |
| Original Closing Date for Applications: | Jul 03, 2019 |
| Current Closing Date for Applications: | Jul 03, 2019 |
| Archive Date: | Aug 08, 2019 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Small businesses Special district governments Private institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) City or township governments Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Independent school districts Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIAMS Research Innovation for Scientific Knowledge (RISK) for Musculoskeletal Diseases initiative focuses on innovative research within the NIAMS mission by encouraging applicants to pursue unusual observations, test imaginative hypotheses, investigate creative concepts, and build ground-breaking paradigms, all of which deviate significantly from the current prevailing theories or practice. This FOA is particularly designed to encourage the submission of projects that are considered too risky, premature, controversial, or unconventional for other NIH mechanisms. This FOA intends to support disease-focused translational studies. We invite research studies aimed at understanding the mechanisms of diseases or conditions relevant to the NIAMS mission, as well as studies aimed at developing or testing diagnostics, therapeutic agents, or preventive interventions up to, but not including, first in human studies. The RISK X02 and R61/R33 FOAs are not intended to support clinical trials. The RISK program will support the two main scientific areas of NIAMS mission, 1) musculoskeletal diseases and 2) the skin and rheumatic diseases. This X02 pre-application and the companion R61/R33 (RFA-AR-19-013) encourage applications related to musculoskeletal diseases. The X02 pre-application is the highly recommended (not required) first step in the application process for the companion R61/R33 (RFA-AR-19-013). Potential applicants should read both FOAs. Investigators whose X02 pre-applications are evaluated to be highly innovative and most relevant to the RISK program will be notified of the opportunity to submit an R61/R33 application under RFA-AR-19-013. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/pa-files/PAR-18-900.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV Email:FBOWebmaster@OD.NIH.GOV |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster FBOWebmaster@OD.NIH.GOV Email: FBOWebmaster@OD.NIH.GOV |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-E | Do not use – must use FORMS-E-REVISED form package | PKG00244363 | Aug 04, 2018 | Aug 24, 2018 | View | |
| FORMS-E-REVISED | FORMS-E-REVISED | PKG00244579 | Sep 04, 2018 | Jul 03, 2019 | View |
Package 1
Mandatory forms
308146 RR_SF424_2_0-2.0.pdf
308146 PHS398_CoverPageSupplement_4_0-4.0.pdf
308146 RR_OtherProjectInfo_1_4-1.4.pdf
308146 PerformanceSite_2_0-2.0.pdf
308146 RR_KeyPersonExpanded_2_0-2.0.pdf
308146 PHS398_ResearchPlan_4_0-4.0.pdf
Optional forms
308146 PHS_AssignmentRequestForm_2_0-2.0.pdf
Package 2
Mandatory forms
308146 RR_SF424_2_0-2.0.pdf
308146 RR_KeyPersonExpanded_2_0-2.0.pdf
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