The National Institute on Drug Abuse (NIDA) is offering this grant to fund research focused on improving the management and implementation of HIV Pre-Exposure Prophylaxis (PrEP) among substance-using populations. Current guidelines acknowledge PrEP for people who inject drugs, but there’s limited systematic data on its effectiveness and adherence in this demographic. This grant aims to address critical research gaps, seeking to understand how substance use impacts PrEP effectiveness and adherence, while also investigating potential unique consequences. Projects should explore new strategies for PrEP implementation and management tailored to substance users. Research is encouraged in states and counties identified by the US Government’s Ending the HIV Epidemic initiative, with justification required for other locales.
Opportunity ID: 334208
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DA-22-017 |
| Funding Opportunity Title: | PrEP for HIV Prevention among Substance Using Populations (R01 – Clinical Trial Optional) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Education Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.279 — Drug Abuse and Addiction Research Programs |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Jun 16, 2021 |
| Last Updated Date: | Jun 16, 2021 |
| Original Closing Date for Applications: | Nov 12, 2021 |
| Current Closing Date for Applications: | Nov 12, 2021 |
| Archive Date: | Dec 18, 2021 |
| Estimated Total Program Funding: | $2,000,000 |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities State governments Native American tribal governments (Federally recognized) For profit organizations other than small businesses County governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Small businesses Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Independent school districts |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | NIDA is interested in research that addresses research gaps related to PrEP and its use among substance users, with the goals of improving PrEP management and implementation. Current US Public Health Service PrEP guidelines recommend PrEP for people who inject drugs (PWID) and mention alcohol and illicit drug use as potential concerns for clinical management. Only one clinical trial has evaluated PrEP among PWID and systematic data regarding the broader use of PrEP among substance users are limited. There is a need to better understand the effects of substance use on PrEP effectiveness and better inform PrEP implementation among substance users. More systematic data are needed regarding the impact of substance use on PrEP management and adherence, along with investigating potential unintended consequences of PrEP use that may be unique to substance users. This RFA is restricted to projects conducted in the United States, although foreign components are permitted where they support domestic research in the United States. Applications are encouraged that propose research in states and counties identified in the US Governments Ending the HIV Epidemic (EtHE) initiative as described here: Ending the HIV Epidemic: A Plan for America https://www.hiv.gov/federal-response/ending-the-hiv-epidemic/overview. Applications to work in locales that are not included in the EtHE initiative must provide an epidemiologic justification for their inclusion in the research. |
| Link to Additional Information: | http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-22-017.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH OER Webmaster grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-G | Use for due dates on or after January 25, 2022 | PKG00269859 | Oct 28, 2021 | Nov 12, 2021 | View | |
| FORMS-F | Use for due dates on or before January 24, 2022 | PKG00267790 | Oct 12, 2021 | Jan 24, 2022 | View |
Package 1
Mandatory forms
334208 RR_SF424_5_0-5.0.pdf
334208 PHS398_CoverPageSupplement_5_0-5.0.pdf
334208 RR_OtherProjectInfo_1_4-1.4.pdf
334208 PerformanceSite_4_0-4.0.pdf
334208 RR_KeyPersonExpanded_4_0-4.0.pdf
334208 PHS398_ResearchPlan_4_0-4.0.pdf
334208 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
334208 RR_Budget_3_0-3.0.pdf
334208 RR_SubawardBudget30_3_0-3.0.pdf
334208 PHS398_ModularBudget_1_2-1.2.pdf
334208 PHS_AssignmentRequestForm_3_0-3.0.pdf
Package 2
Mandatory forms
334208 RR_SF424_2_0-2.0.pdf
334208 PHS398_CoverPageSupplement_5_0-5.0.pdf
334208 RR_OtherProjectInfo_1_4-1.4.pdf
334208 PerformanceSite_2_0-2.0.pdf
334208 RR_KeyPersonExpanded_2_0-2.0.pdf
334208 PHS398_ResearchPlan_4_0-4.0.pdf
334208 PHSHumanSubjectsAndClinicalTrialsInfo_2_0-2.0.pdf
Optional forms
334208 RR_Budget_1_4-1.4.pdf
334208 RR_SubawardBudget30_1_4-1.4.pdf
334208 PHS398_ModularBudget_1_2-1.2.pdf
334208 PHS_AssignmentRequestForm_3_0-3.0.pdf
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