This grant, offered by NIDDK and NIAID, is for fostering new multi-disciplinary teams to mechanistically investigate how HIV comorbidities and co-infections interact with viral reservoirs. The primary purpose is to understand how these interactions may complicate current HIV cure strategies, whether aimed at sustained viral suppression or viral elimination. Successful proposals will explore the impact of inflammation, metabolic perturbations, and other pathophysiological processes associated with these conditions on reservoir dynamics. Researchers should also focus on the interplay of these comorbidities and co-infections on HIV reservoir biology, especially concerning their relevance to potential cure approaches. This initiative seeks to deepen our understanding of these complex biological interactions to advance HIV cure research.
Opportunity ID: 352698
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-25-013 |
| Funding Opportunity Title: | Impact of Comorbidities and Co-Infections on HIV Reservoirs (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.313 — NIH Office of Research on Women’s Health |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Feb 29, 2024 |
| Last Updated Date: | Feb 29, 2024 |
| Original Closing Date for Applications: | Jul 30, 2024 |
| Current Closing Date for Applications: | Jul 30, 2024 |
| Archive Date: | Sep 04, 2024 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | – |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Others (see text field entitled “Additional Information on Eligibility” for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities County governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Special district governments Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education State governments City or township governments Private institutions of higher education Small businesses |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This Notice of Funding Opportunity (NOFO) seeks to foster new multi-disciplinary teams to address how HIV Comorbidities and co-infections within the missions of NIDDK and NIAID interact with viral reservoirs, potentially confounding cure strategies aimed at either sustained viral suppression or elimination from the body. These teams will mechanistically interrogate the impact of inflammation, metabolic perturbations, or other pathophysiological processes associated with these comorbidities or co-infections on reservoir dynamics, and/or the interplay of these conditions and co-infections on HIV reservoir biology in ways that are likely to interact with potential cure strategies. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-25-013.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 352698 Full Announcement-RFA-DK-25-013 -> RFA-DK-25-013-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00285113 | Jun 30, 2024 | Jul 30, 2024 | View |
Package 1
Mandatory forms
352698 RR_SF424_5_0-5.0.pdf
352698 PHS398_CoverPageSupplement_5_0-5.0.pdf
352698 RR_OtherProjectInfo_1_4-1.4.pdf
352698 PerformanceSite_4_0-4.0.pdf
352698 RR_KeyPersonExpanded_4_0-4.0.pdf
352698 PHS398_ResearchPlan_5_0-5.0.pdf
352698 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
352698 RR_Budget_3_0-3.0.pdf
352698 RR_SubawardBudget30_3_0-3.0.pdf
352698 PHS398_ModularBudget_1_2-1.2.pdf
352698 PHS_AssignmentRequestForm_3_0-3.0.pdf
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