This NIDDK grant supports Ancillary Studies, leveraging resources from its Inflammatory Bowel Disease Genetics Consortium (IBDGC). While the IBDGC has identified over 250 IBD susceptibility loci, their underlying biological mechanisms often remain unknown. This grant aims to expand the functional investigation of IBD susceptibility loci, causal variants, effector genes, and related phenotypes. Proposed studies must focus on identifying causal variants or characterizing effector genes within IBD risk loci. Utilizing the IBDGC’s established subjects, samples, and datasets, the research must not duplicate ongoing or completed IBDGC efforts.
Opportunity ID: 345103
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-22-023 |
| Funding Opportunity Title: | Ancillary Studies to the NIDDK Inflammatory Bowel Disease Genetics Consortium (R01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Grant |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Dec 23, 2022 |
| Last Updated Date: | Dec 23, 2022 |
| Original Closing Date for Applications: | Nov 08, 2023 |
| Current Closing Date for Applications: | Nov 08, 2023 |
| Archive Date: | Dec 14, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $300,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | For profit organizations other than small businesses Public and State controlled institutions of higher education Independent school districts City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Others (see text field entitled “Additional Information on Eligibility” for clarification) Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities County governments Private institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC), in collaboration with the International IBD Genetics Consortium, has identified over 250 susceptibility loci for IBD. The IBDGC has recently been renewed with a continued mission to characterize the genetic architecture of IBD phenotypes in diverse populations and to elucidate the biological mechanisms by which genetic variants influence IBD pathophysiology and clinical course. However, current resources permit functional investigation of only a limited number of loci, genes and physiological domains, while the biological mechanisms underlying most of the identified IBD risk loci remain unknown. The purpose of this Funding Opportunity Announcement (FOA) is to expand the number of IBD susceptibility loci, causal variants and effector genes, and IBD-related phenotypes and physiological domains under investigation via Ancillary Studies utilizing the extensive resources including subjects, samples and datasets established by the IBDGC. Proposed Ancillary Studies should focus on causal variant identification and/or functional characterization of effector genes within IBD risk loci and must not duplicate studies either ongoing or already completed by the IBDGC. |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-22-023.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
There are no related documents on this grant.
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00279039 | Feb 09, 2023 | Nov 08, 2023 | View |
Package 1
Mandatory forms
345103 RR_SF424_5_0-5.0.pdf
345103 PHS398_CoverPageSupplement_5_0-5.0.pdf
345103 RR_OtherProjectInfo_1_4-1.4.pdf
345103 PerformanceSite_4_0-4.0.pdf
345103 RR_KeyPersonExpanded_4_0-4.0.pdf
345103 PHS398_ResearchPlan_5_0-5.0.pdf
345103 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
345103 RR_Budget_3_0-3.0.pdf
345103 RR_SubawardBudget30_3_0-3.0.pdf
345103 PHS398_ModularBudget_1_2-1.2.pdf
345103 PHS_AssignmentRequestForm_3_0-3.0.pdf
Share This Post, Choose Your Platform!
About the Author: osnqt
