This NIDDK grant invites applications for the Gut-Brain Communication in Parkinson’s Disease Consortium (GBPDC). Its primary objective is to accelerate research on the role of gastrointestinal symptoms and gut-brain communication in the initiation and pathogenesis of Parkinson’s disease, facilitating the development of innovative early-phase GI-based diagnostic tools and biomarkers for PD. The initiative aims to establish a clinical research network with a Coordinating Center, recruiting diverse patient cohorts (PD, at-risk, healthy controls) for standardized data and biospecimen collection. The GBPDC will foster collaboration by sharing data, biomaterials, and resources among projects and making them publicly available, ultimately advancing understanding of PD. Research addressing sex/gender differences and diversity is highly encouraged.
Opportunity ID: 349669
General Information
| Document Type: | Grants Notice |
| Funding Opportunity Number: | RFA-DK-22-036 |
| Funding Opportunity Title: | A Consortium for Gut-Brain Communication in Parkinsons Disease (U01 Clinical Trial Not Allowed) |
| Opportunity Category: | Discretionary |
| Opportunity Category Explanation: | – |
| Funding Instrument Type: | Cooperative Agreement |
| Category of Funding Activity: | Food and Nutrition Health |
| Category Explanation: | – |
| Expected Number of Awards: | – |
| Assistance Listings: | 93.847 — Diabetes, Digestive, and Kidney Diseases Extramural Research |
| Cost Sharing or Matching Requirement: | No |
| Version: | Synopsis 1 |
| Posted Date: | Aug 01, 2023 |
| Last Updated Date: | Aug 01, 2023 |
| Original Closing Date for Applications: | Nov 15, 2023 |
| Current Closing Date for Applications: | Nov 15, 2023 |
| Archive Date: | Dec 21, 2023 |
| Estimated Total Program Funding: | – |
| Award Ceiling: | $300,000 |
| Award Floor: | – |
Eligibility
| Eligible Applicants: | Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Small businesses Native American tribal governments (Federally recognized) For profit organizations other than small businesses Public and State controlled institutions of higher education Others (see text field entitled “Additional Information on Eligibility” for clarification) County governments City or township governments Independent school districts Private institutions of higher education Special district governments Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education |
| Additional Information on Eligibility: | Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed. |
Additional Information
| Agency Name: | National Institutes of Health |
| Description: | This FOA invites new applications to participate in the Gut-Brain Communication in Parkinsons Disease (PD) Consortium (GBPDC). The goals of this initiative are 1) to establish a network of individual research projects and a Coordinating Center focused on clinical research; 2) recruitment of sufficient patients and use of standardized protocols to collect data and biospecimens relevant to both neurology and gastroenterology research on PD; 3) share data, biomaterials, models, reagents, resources and methods among projects in the GBPD; and 4) make these publicly available through the Coordinating Center. The objective of this consortium is to accelerate research on the role gastrointestinal (GI) symptoms and changes in gut-brain communication in the initiation and pathogenesis of Parkinsons disease in order to facilitate development and validation of innovative early-phase GI-based diagnostic tools and biomarkers for PD. The research centers of the GBPDC will serve as sites for enrollment of PD patients with and without GI symptoms, patients with GI symptoms considered to be at risk for PD, and healthy age-matched controls for laboratory-based studies on biological samples obtained from these patients. The NIDDK strongly encourages Research on Sex/Gender Differences, Sexual and Gender Minority-Related Research and Race/Ethnic Diversity (see NOT-DK-22-003). |
| Link to Additional Information: | https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-22-036.html |
| Grantor Contact Information: | If you have difficulty accessing the full announcement electronically, please contact:
NIH Grants Information
grantsinfo@nih.gov Email:grantsinfo@nih.gov |
Version History
| Version | Modification Description | Updated Date |
|---|---|---|
Related Documents
Folder 349669 Full Announcement-RFA-DK-22-036 -> RFA-DK-22-036-Full-Announcement.pdf
Packages
| Agency Contact Information: | NIH Grants Information grantsinfo@nih.gov Email: grantsinfo@nih.gov |
| Who Can Apply: | Organization Applicants |
| Assistance Listing Number | Competition ID | Competition Title | Opportunity Package ID | Opening Date | Closing Date | Actions |
|---|---|---|---|---|---|---|
| FORMS-H | Use for due dates on or after January 25, 2023 | PKG00282742 | Oct 16, 2023 | Nov 15, 2023 | View |
Package 1
Mandatory forms
349669 RR_SF424_5_0-5.0.pdf
349669 PHS398_CoverPageSupplement_5_0-5.0.pdf
349669 RR_OtherProjectInfo_1_4-1.4.pdf
349669 PerformanceSite_4_0-4.0.pdf
349669 RR_KeyPersonExpanded_4_0-4.0.pdf
349669 PHS398_ResearchPlan_5_0-5.0.pdf
349669 PHSHumanSubjectsAndClinicalTrialsInfo_3_0-3.0.pdf
Optional forms
349669 RR_Budget_3_0-3.0.pdf
349669 RR_SubawardBudget30_3_0-3.0.pdf
349669 PHS398_ModularBudget_1_2-1.2.pdf
349669 PHS_AssignmentRequestForm_3_0-3.0.pdf
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